Research

Jordan Wright, MD, PhD, left, and Adel Eskaros, MBBS, PhD, are lead authors of the report on pancreatic exocrine-endocrine “crosstalk.” (photo by Susan Urmy)

Pancreas “crosstalk” may influence course of Type 1 and Type 2 diabetes

In the largest study of its kind, researchers at Vanderbilt have identified unexpected alterations in the exocrine tissues of the pancreas that occur in the two major forms of diabetes, and with aging and obesity.

Polygenic “scores” may improve cancer screening

Accounting for genetic variability in biomarkers not associated with cancer risk could avoid unnecessary diagnostic procedures, Vanderbilt researchers found.

Crowe, Osheroff honored by AAMC

Vanderbilt’s James E. Crowe, Jr, MD, and Neil Osheroff, PhD, are among 12 individuals honored by the Association of American Medical Colleges during its 2023 Awards Recognition Event.

Randika “Randy” Perera, PhD, left, Wenhan Zhu, PhD, Walter Chazin, PhD, Luisella Spiga, PhD, Ryan Fansler and colleagues discovered that beneficial bacteria in the gut impact the competition that occurs between host cells and pathogens for the essential nutrient iron. (photo by Erin O. Smith)

Study discovers role for gut bacteria in host-pathogen competition for nutrients

Vanderbilt research shows that commensal gut microbes impact the host-pathogen competition for iron and has implications for therapeutic strategies aimed at preventing pathogens from acquiring essential nutrients.

Alyssa Hasty, PhD, left, Jeffrey Rathmell, PhD, and Kamran Idrees, MD, MSCI, are part of a multidisciplinary team that received a 2023 Endeavor Award from The Mark Foundation for Cancer Research to study the connection between obesity and cancer. Team members not pictured include Kathryn Wellen, PhD, Liza Makowski, PhD, and Kathryn Beckermann, MD, PhD.

Vanderbilt-led team receives 2023 Endeavor Award from The Mark Foundation for Cancer Research

A multidisciplinary team of investigators has received a 2023 Endeavor Award from The Mark Foundation for Cancer Research to support four closely linked projects exploring the fundamental mechanisms that drive the obesity-cancer connection,

VUMC scientists record powerful signal in the brain’s white matter

Vanderbilt researchers report that when people who are having their brains scanned by fMRI perform a task, like wiggling their fingers, certain signals increase in white matter throughout the brain, which has long been thought to play a lesser role the more the brain’s more energetic gray matter.

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