statins

The study could suggest ways to promote the transport of phospholipids and cholesterol out of macrophages, immune system cells that play key roles in all stages of atherosclerosis development.
March 23, 2023

Reminders for clinicians improve prescribing for high cholesterol

A Vanderbilt study found that automated targeted reminders for clinicians helped increase prescribing of high intensity statins for patients with various atherosclerotic cardiovascular disease diagnoses, including coronary or peripheral artery disease and ischemic stroke.

By Paul Govern
July 12, 2021

Probing statin-associated diseases with genetics

Vanderbilt researchers used genetics tools and biobanks with linked electronic health records to explore the associations between statins and noncardiovascular diseases.

By Leigh MacMillan
Amanda Mixon, MD, MS
November 17, 2020

Statins to be studied for prevention of dementia, disability and heart disease 

Vanderbilt University Medical Center researchers are enrolling adults aged 75 and over to study whether taking atorvastatin, a drug commonly used to lower cholesterol also called Lipitor®, can help maintain health by preventing dementia, disability, and heart disease.

By Craig Boerner
May 7, 2018

Records point to drug-drug interaction

Patients who take a cholesterol-lowering statin drug while taking the antibiotic daptomycin have increased risk of developing muscle weakness or a more severe form of muscle damage.

By Paul Govern
May 3, 2018

Gene study spots clues to heart risk for statin patients

A Vanderbilt-led research team has discovered genetic variations that increase the risk of heart attack even when patients are receiving a statin drug like Lipitor or Crestor to lower their blood cholesterol.

By Bill Snyder
January 17, 2018

HDL and kidney injury after surgery

Higher concentrations of high-density lipoproteins — HDL, the “good” cholesterol — may be protective against acute kidney injury after cardiac surgery, Vanderbilt researchers have discovered.

By Jenelle Grewell
February 23, 2016

VUMC study finds statins do not ease kidney injury following cardiac surgery

By Paul Govern
April 16, 2015

Study shows statin use improves renal cell cancer survival

A new study led by Vanderbilt University investigators found that patients being treated with statins at the time of surgery for kidney cancer, also known as renal cell carcinoma, had improved overall survival and disease-specific survival.
By VUMC News and Communications
March 31, 2014

E-records shed light on drug response

Electronic medical records linked to DNA biobanks are a valid resource for defining and understanding the genetic factors that contribute to drug response.
By Leigh MacMillan
October 4, 2012

PREDICT helps pinpoint right statin for patient

When O.T. Hayes, 67, of Lebanon, Tenn., first starting seeing his cardiologist, David Hansen, M.D., for treatment of his coronary artery disease, it was hard to predict which of the various medications available would help control Haynes’ high cholesterol.
By Kathy Whitney
October 28, 2011

Vanderbilt doctors to screen patients taking statins for genetic risk factors

Vanderbilt University Medical Center doctors announced today they will begin screening patients who take commonly prescribed statin drugs for a rare genetic variation that can increase risks for side effects from these drugs such as muscle aches, kidney damage and even death.
By Craig Boerner