structural biology

How ABC transporters move molecules

New views of how transporters move molecules across cell membranes are key to understanding how these proteins impact tumor cell drug resistance and inherited diseases such as cystic fibrosis.

Antibacterial protein’s molecular workings revealed

Vanderbilt investigators report new insights to the workings of calprotectin, an immune system protein that “starves” bacterial pathogens of the metal nutrients they require.

New view of DNA processing ‘hub’

Structural studies reveal a new framework for understanding a central player in DNA processing.

Seeing light receptor’s interactions

Understanding how the main receptor for light interacts with other signaling molecules may inform new pharmaceutical development.

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