transporter Archive — Page 1 of 1

3D histological illustration of a row of tall columnar epithelial cells, with elongated nuclei and a brush-like apical surface above a purple underlying layer.
November 7, 2022

Gene mutations impair gut barrier

Mutations in a cell membrane transporter protein impair the integrity of the gut lining, contributing to chronic gastrointestinal distress for people with the mutations, Vanderbilt researchers report.

Stylized glowing human brain surrounded by bright white-blue electrical lightning against a dark blue background.
October 6, 2022

Gene tied to childhood epilepsy

Data drawn from four unrelated patients with a childhood epilepsy syndrome — and from in vitro and in vivo studies — link novel variants in a GABA transporter gene to seizure activity, Vanderbilt researchers reported.

Stylized medical illustration of intertwined intestinal loops glowing orange and red against a dark blue abdominal silhouette, with scattered dark circular markings on the intestines.
April 16, 2020

Transporter’s role in gut barrier

A disease-associated mutation in a transporter protein impairs gut barrier function, leading to gastrointestinal disease and chronic infections.

Close-up of analog electricity meters with black needles and numbered dials, labeled “KILOWATT.”
February 20, 2020

Transporter mutation alters cell energy

A disease-associated mutation in a transporter protein causes cells to increase energy production, as if they are starving, Vanderbilt researchers have discovered.

Brain image
November 14, 2019

Blueprint for treating epilepsy

Structural details of a protein that is essential to normal brain function could improve treatments for epilepsy and other seizure disorders.

Stylized 3D visualization of a glowing purple synapse, with two bulbous nerve endings separated by a bright gap and surrounded by smaller synaptic structures.
July 24, 2019

Defective transporter linked to autism

A first-of-its-kind mouse model may help reveal mechanistic underpinnings for the altered behaviors of autism spectrum disorder.