type 2 diabetes

Insulin in vials
November 11, 2021

New way to bEET insulin resistance

Signaling molecules called EETs could improve insulin resistance, a primary risk factor for Type 2 diabetes and cardiovascular disease, Vanderbilt researchers have discovered.

By Bill Snyder
August 5, 2021

Gene expression in diabetic nephropathy

Vanderbilt researchers are looking to mRNA populations in podocytes — kidney cells that help filter blood — to help identify potential targets for treating diabetic kidney disease.

By Shivani Sharma
Shichun Bao, MD, PhD, center, and Brenda Weedman, RN, BSN, discuss continuous glucose monitors with patient Sherry Neergaard.
July 15, 2021

Study shows continuous glucose monitors improve management of type 2 diabetes

For patients with type 2 diabetes treated with basal or long-acting insulin, the use of continuous glucose monitors (CGMs) can result in significantly lower hemoglobin A1C (a blood test that reflects average blood glucose levels over three months), and better management of the disease according to a study recently published in the journal JAMA.

By Jill Clendening
May 20, 2021

Type 2 diabetes medication shown to benefit asthma patients

Type 2 diabetes patients who also have asthma are benefitting from a diabetes medication, typically given to help the pancreas produce more insulin, that also improves asthma symptoms and may reduce lung and airway inflammation.

By Craig Boerner
Insulin in vials
February 18, 2021

Gene variant and glucose metabolism

Genetic variation that impacts glucose- and insulin-related signaling affects responses to type 2 diabetes treatments and warrants further study.

By Leigh MacMillan
November 17, 2020

A cohort for type 2 diabetes studies

A study group of more than 600,000 patients with type 2 diabetes, identified from electronic medical records in the PCORnet national research network, could be valuable for assessing the safety of type 2 diabetes drugs.

By Leigh MacMillan
December 18, 2019

Telehealth grant boosts diabetes prevention efforts

Vanderbilt’s Diabetes Prevention Program (DPP) has demonstrated its effectiveness at helping employees lose weight as a means of preventing Type 2 diabetes and has received a five-year grant from the National Institutes of Health (NIH) to expand the program using telehealth.
By Wayne Wood
December 4, 2019

Genetic screen in worms reveals critical step in insulin synthesis

The identification of a protein important for insulin synthesis may hold clues for understanding the pathogenesis of diabetes.
By Leigh MacMillan
October 3, 2019

Diabetes drug study explores cardiovascular risks for patients with kidney disease

An observational study using medical record information from nearly 50,000 U.S. military veterans sheds new light on which drugs are best for patients with Type 2 diabetes and one of its common complications, kidney disease.
By Paul Govern
September 14, 2018

Diabetes drug may prevent cancer

The research suggests that metformin should be further studied clinically for the prevention of liver cancer.
By VUMC News and Communications
September 6, 2018

Team’s findings could spur new treatments for type 2 diabetes

An international research team including scientists from Vanderbilt University has discovered how the diabetes drug metformin blocks glucose production by the liver. The discovery, reported Aug. 27 in the journal Nature Medicine, could lead to development of new ways to treat type 2 diabetes.
By Bill Snyder
July 12, 2018

Team explores diabetes drug’s ability to treat RSV infection

A drug used to treat diabetes may point to new therapies for respiratory syncytial virus (RSV) bronchiolitis — inflammation and obstruction of the lungs’ small airways. A multi-disciplinary team of Vanderbilt investigators has demonstrated that liraglutide reduces the inflammatory response to RSV infection in a mouse model of the disease.
By Leigh MacMillan
January 25, 2018

Study may point to new ways to reverse insulin resistance

Researchers at Vanderbilt University have discovered how insulin crosses the capillary endothelium to exit blood vessels and stimulate skeletal muscle cells — a major finding that may lead to new ways to reverse insulin resistance, a hallmark of type 2 diabetes.
By Bill Snyder
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