VANTAGE

April 25, 2023

COVID alters respiratory microbiota

COVID-19 infection alters the microbes of the upper respiratory tract for at least several weeks, and such disturbances could impact disease severity and be targets for therapeutic interventions.

By Leigh MacMillan
VUMC’s new automated biobanking system can store as many as 10 million biospecimens.
August 25, 2022

New high-tech biobank safeguards critical specimens

By Bill Snyder
The study team included, from left, Mohammad Saleem, PhD, Lale Ertuglu, MD, Annet Kirabo, PhD, and Ashley Pitzer, PhD.
August 17, 2022

Researchers discover how salt increases blood pressure

A Vanderbilt research team has discovered that activation of a certain protein complex involved in the inflammatory response in immune cells contributes to salt-sensitive hypertension.

By Leigh MacMillan
Contributors to the COVID-19 microbiome study include (front row, from left) Julie Bastarache, MD, Meghan Shilts, MS, MHS, (middle row, from left) Jodell Jackson, PhD, Suman Das, PhD, Angela Jones, MS, (back row, from left) Jonathan Schmitz, PhD, MD, Simon Mallal, MBBS, and Jordan Best, PhD.
March 11, 2021

‘Friendly’ bacteria may impact COVID severity

The U.S. Centers for Disease Control and Prevention (CDC) has awarded Vanderbilt University Medical Center a two-year, $3.7-million contract to determine genetic and bacterial factors that may increase the risk for severe illness and death from COVID-19.

By Bill Snyder
April 9, 2020

Study tracks genomics of lung tumor behavior

A study by Vanderbilt researchers has identified genomic alterations in early stage adenocarcinomas of the lung that may indicate whether the lesions develop into aggressive tumors.

By Tom Wilemon
August 3, 2017

HDAC3 role in B-cell development

The histone deacetylase HDAC3 is required for the maturation of B cells, white blood cells that produce antibodies.

By Leigh MacMillan
August 6, 2015

Genotyping project to be an ‘engine of discovery’

Vanderbilt University researchers next month will launch a major initiative to acquire “dense genotypes” from 100,000 individuals whose medical histories are known.
By Bill Snyder
January 29, 2015

Core facilities key driver of VUMC research gains

During the past five years, Vanderbilt University Medical Center has become a leader in “personalized medicine,” the use of genomic information to individualize patient care.
By Bill Snyder
April 25, 2013

VANTAGE point

Travis Clark, Ph.D., technical director of Sequencing in the VANTAGE core laboratories, shows a tour group how DNA fragments are loaded onto “flow cells” for reading by “next-generation” sequencing machines.
By VUMC News and Communications
February 7, 2013

Study tracks genes involved in heart rhythm disorders

A team led by Vanderbilt University investigators has discovered two new genes — both coding for the signaling protein calmodulin — associated with severe early-onset disorders of heart rhythm.
By Leigh MacMillan
November 1, 2012

Genomic research gains ad-“vantage” with new resources

Vanderbilt University Medical Center has stepped up its support of research aimed at cracking the mysteries of the genome, the master DNA code.
By Bill Snyder