VI4

July 9, 2020

Recurrent UTIs linked to hidden reservoir

Bacterial invasion of vaginal cells sets up a protective niche and a reservoir for recurrent urinary tract infections, Vanderbilt researchers demonstrated.

By Sarah E. Glass
July 9, 2020

VUMC’s Byndloss recognized for microbiome research

Mariana Byndloss, DVM, PhD, assistant professor of Pathology, Microbiology and Immunology, has been selected as a runner-up of the inaugural NOSTER & Science Microbiome Prize.

By Leigh MacMillan
Jeff Balser, MD, PhD, left, Jennifer Pietenpol, PhD, and Eric Skaar, PhD, pose for a photo during a recent tour of new space for the Vanderbilt Institute for Infection, Immunology and Inflammation.
July 9, 2020

New space bolsters infectious disease and immunology discovery

The Vanderbilt Institute for Infection, Immunology and Inflammation (VI4) recently moved into its new research and administrative home.

By Leigh MacMillan
June 24, 2020

Vanderbilt Institute for Infection, Immunology and Inflammation holds third annual symposium

The Vanderbilt Institute for Infection, Immunology and Inflammation (VI4) held its third annual symposium last week as a virtual, on-line event to preserve social distancing during COVID-19.

By Bill Snyder
June 10, 2020

C. diff captures blood cell cofactor to build defensive shield

Vanderbilt University Medical Center scientists have identified a C. diff protein system that senses and captures heme (part of hemoglobin) to build a protective shield that fends off threats from our immune system and antibiotics.

By Leigh MacMillan
Jim Cassat, MD, PhD, and colleagues are studying enzymes involved in metabolism that are particularly important for Staphylococcus aureus to survive in host tissues.
June 3, 2020

Study explores how staph bacteria can survive in bone

A comprehensive evaluation of the metabolic pathways that support Staphylococcus aureus (“staph”) growth during invasive bone infections could offer new targets for treatment.

By Leigh MacMillan
May 14, 2020

The adaptable anthrax bacterium

Vanderbilt researchers discover how anthrax bacterium defends itself against structural damage and resists the toxicity of the antimicrobial drug targocil.
By Leigh MacMillan
February 25, 2020

Looking through MudPIT for protein interactions

The identification of novel protein interactions and sites of modification in proteins involved in mRNA translation adds to understanding of a process that is an important therapeutic target.
By Sanjay Mishra
February 12, 2020

Allergic diseases expert Locksley set for Discovery Lecture

Richard Locksley, MD, director of the Sandler Asthma Basic Research Center at the University of California, San Francisco, will deliver the next Flexner Discovery Lecture on Thursday, Feb. 20.
By Leigh MacMillan
February 6, 2020

Powering H. pylori pathogenesis

Timothy Cover and colleagues report new insights into the sources of energy used by a bacterial “machine” linked to the pathogenesis of stomach cancer.
By Leigh MacMillan
January 13, 2020

Zinc uptake by a deadly pathogen

The increasingly antibiotic-resistant bacterium Acinetobacter baumannii requires zinc to cause infection, and Vanderbilt researchers have identified the zinc uptake system it uses.
By Leigh MacMillan
December 12, 2019

Wexler receives Helen Hay Whitney Foundation Fellowship

Aaron Wexler, PhD, a research fellow in the Department of Pathology, Microbiology and Immunology, has received a Helen Hay Whitney Foundation Fellowship.
By Leigh MacMillan
October 31, 2019

Imaging host-pathogen battle for metal

An unprecedented view of bacterial products within infected tissues opens new opportunities to explore infection biology and devise novel therapeutic strategies.
By Leigh MacMillan
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