Cancer

Sam Chang, MD, MBA, has been named chief surgical officer at Vanderbilt-Ingram Cancer Center (VICC), a new leadership position responsible for advancing excellence in surgical care in cancer patients, expanding service locations, maximizing resource efficiencies and maintaining high-quality standards among other duties.

Combining two drugs reduced colorectal cancer cell growth in vitro and in an animal model, suggesting the combination may be a promising treatment for patients.

Vanderbilt scientists have discovered a new target for normalizing tumor blood vessels to improve cancer immunotherapies.

Patients with ALK-positive non-small cell lung cancer treated with ensartinib fared better and lived longer than those who received crizotinib, according to results of a phase 3 study.

A computational technique that combines the effect of multiple genomic variants has the potential to identify high-risk individuals for cancer prevention.

Deborah Lannigan and colleagues identify a key regulator of the estrogen receptor and suggest that its downregulation by oral contraceptives may increase oxidative stress and DNA damage, a common cause of cancer.

The first study of appendiceal cancer patterns and survival by race/ethnicity among patients younger than 50 in the U.S. showed survival disparities.