Cancer

January 25, 2021

An interacting factor in leukemia

A blood stem cell protein plays a role in the initiation and progression of leukemia, Vanderbilt researchers have found.

By Anivarya Kumar
January 7, 2021

Vitamin D activation and cancer risk

Vitamin D protection against colon cancer varies according to parathyroid hormone response, particularly among women.

By Paul Govern
December 22, 2020

Arthritis drug may treat immunotherapy-related heart complication

By Tom Wilemon
Ann Richmond, MD, Chi Yan, PhD, Jinming Yang, PhD, and colleagues are studying ways to boost antitumor immunity and reduce tumor growth in breast cancer and melanoma.
December 17, 2020

Study reveals new strategy for reducing tumor growth, metastasis

A team of Vanderbilt investigators has discovered that blocking a certain signaling pathway boosts antitumor immunity and reduces tumor growth and metastasis in models of breast cancer and melanoma.

By Leigh MacMillan
December 17, 2020

Study reveals distinct genomic landscape for young adults with appendiceal cancer

The first study to compare molecular landscapes of early-onset and late-onset appendiceal cancer has revealed distinct non-silent mutations in the tumors of younger patients, setting the stage for the development of potential therapeutic advances for this rare disease.

By Tom Wilemon
James Crowe Jr., MD, and colleagues are exploring how the body’s immune system gears up to fight off infection.
December 1, 2020

Vanderbilt University Medical Center’s Crowe receives 2020 “Golden Goose” Award for COVID-19 research

James Crowe Jr., MD, a physician-scientist at Vanderbilt University Medical Center who has pioneered development of human monoclonal antibodies as potential treatments for viral diseases, has won a 2020 “Golden Goose” Award.

By Bill Snyder
November 23, 2020

Hot spots identified for colorectal cancer mortality rates among young women

Women diagnosed with early-onset colorectal cancer have a greater risk of dying from the disease depending upon their county of residence, according to a study published in Clinical and Translational Gastroenterology.
By Tom Wilemon
November 18, 2020

V Scholar Award to support Byndloss’ cancer research

Mariana Byndloss, DVM, PhD, assistant professor of Pathology, Microbiology and Immunology, has received a V Scholar Award to support her studies of the links between obesity, the gut microbiome and colorectal cancer.
By Leigh MacMillan
November 18, 2020

New drug for metastatic colorectal cancer enters phase 3 trial

A new therapy for metastatic colorectal cancer that has been granted fast track designation by the U.S. Food and Drug Administration is being tested in a phase 3 clinical trial at Vanderbilt-Ingram Cancer Center.
By Tom Wilemon
November 12, 2020

New therapeutic target for lung cancer

Vanderbilt researchers have identified a new molecular partner — and potential therapeutic target — in a signaling axis that drives lung cancer.
By Sarah E. Glass
November 12, 2020

Breast cancer treatment in older women

A new study from Vanderbilt epidemiologists suggests that it’s time to reconsider clinical practice guidelines for the treatment of early-stage breast cancer in older women.
By Leigh MacMillan
November 10, 2020

Study underscores importance of personalized medicine in kidney cancer

A new study sheds light on how molecular subsets within the tumors of kidney cancer patients determine treatment outcomes and underscores the importance of personalized medicine in making therapy decisions.
By Tom Wilemon
November 5, 2020

Screening younger women for hereditary cancers may be cost effective

Population-wide screening for genetic variants linked to hereditary breast and ovarian cancer may be cost effective in women between the ages of 20 and 35, according to a study published in JAMA Network Open.
By Tom Wilemon