Cancer

A group of Vanderbilt researchers has used laser technology and a custom-built multiphoton microscope to distinguish breast cancer subtypes and determine if specific therapies are working against the cancer cells in as little as two days.

Understanding the regulation of mutant EGF receptors commonly found in lung cancers could lead to new targeted therapies.

Molecular characterization of pre-cancerous changes in cells lining the stomach could point to lesions with a greater risk of progression to cancer.

Emmanuel Volanakis, M.D., assistant professor of Pediatrics and Hematology/Oncology, was awarded a $250,000 Hyundai Hope On Wheels grant last week for his ongoing research into T-cell acute lymphoblastic leukemia (ALL), an aggressive blood cancer.

Vanderbilt investigators have combined next-generation sequencing technologies and bioinformatics analyses to screen for genome-wide genetic mutations associated with drug resistance in a series of lung cancer cell lines.

A newly identified factor regulates blood vessel growth in colorectal tumors and could be a promising target for cancer therapies.

The nuclear receptor TR3 contributes to ovarian cancer cell death in response to platinum-based chemotherapy – and may be a good target for overcoming cell resistance to certain treatments.