The study found that West African genetic ancestry was associated with shorter disease-free survival, particularly for women with hormone receptor-positive/human epidermal growth factor receptor 2-negative breast cancer.

Preliminary results of a clinical trial of 4-phenylbutyrate (PBA) “show a significant reduction in seizure activity among participants.”

The study revealed overlapping genetic underpinnings between rhythm-related skills and language-related traits, including dyslexia.

VUMC researchers applied the new approach to large GWAS datasets for breast, prostate and lung cancers, and three brain disorders.

Research could lead to improved diagnosis and the first effective treatment for the disorder, called “clonal hematopoiesis of indeterminate potential,” or CHIP. 

Evaluating how genetic risk interacts with environmental risk factors such as sexual trauma is important for understanding how mental illness develops and identifying high-risk groups for early intervention.

The report supports previous clinical trials that found the GLP-1 receptor agonist drug semaglutide reduced kidney disease progression in patients with Type 2 diabetes.