Genetics & Genomics Archive

October 30, 2025

Genetic variation impact scores: A new tool for earlier heart disease detection

The study will go a long way to improving the early diagnosis and treatment of familial hypercholesterolemia, a common genetic driver of cardiovascular disease.

“The Gout” by British artist James Gillray is a hand-colored soft-ground etching from 1799 and is in the collection of the Metropolitan Museum of Art. (public domain)
October 29, 2025

New genetic marker found to predict severe gout drug reactions in US patients

The discovery could improve safety of allopurinol for millions by expanding genetic screening.

October 23, 2025

New resources help people take action to prevent inherited diseases

To launch a connection search, someone with a specific gene variant signs up to meet others who share that variant, beginning a process of discovering new connections with unknown relatives and encouraging family members to get tested.

October 15, 2025

New NCI-funded project targets polyp recurrence to prevent colon cancer

The researchers anticipate that their findings will inform personalized colorectal polyp surveillance, guide therapeutic prevention strategies, and ultimately reduce the burden of colorectal cancer nationwide.

Dan Roden, MD, chats with colleagues during a break in the symposium. (photo by Erin O. Smith)
October 1, 2025

Symposium honors personalized medicine leader Dan Roden

Roden is internationally known for his contributions to understanding arrhythmias and to the field of pharmacogenomics.

(Shutterstock)
September 29, 2025

Keloid risk genes open door to better therapy

These raised scars tend to recur after surgical removal, and the effectiveness of alternative treatments is limited.