Severe obesity — a condition of being 100 pounds or more overweight — has doubled in the United States over the past two decades to 9.2%, with the greatest increases among women and Latino populations.

The Vanderbilt Genetics Institute is the intellectual hub for genomics research at Vanderbilt University Medical Center and Vanderbilt University.

The milestone creates one of the largest, most comprehensive clinical genomic datasets of its kind; multiomic data to be added in next phase of program.

Sarah Tishkoff described her groundbreaking research during a talk titled “African Evolutionary Genomics: Reconstructing Human Evolution and the Genetic Basis of Complex Adaptive Traits.”

Tishkoff's groundbreaking research at the University of Pennsylvania has broad implications for understanding and treating human disease.

The research could point to future therapeutic strategies that treat PF patients based on their individual stage of cellular and molecular remodeling.

The study identified 332 independent association signals for breast cancer risk, including 131 signals not previously reported.