Pharmacogenomics & Precision Medicine

February 19, 2024

VUMC part of major step to achieving precision medicine

An analysis of genomic data from nearly 250,000 participants in the National Institutes of Health’s All of Us Research Program has identified more than 275 million previously unreported genetic variations, nearly 4 million of which have potential health consequences.

By Bill Snyder
VUMC’s new automated biobanking system can store as many as 10 million biospecimens.
June 8, 2022

BioVU celebrates 15 years supporting personalized medicine

BioVU is celebrating its 15th year and has enabled hundreds of studies and publications exploring the genetic underpinnings of a host of conditions including cancer, heart disease and diabetes. 

By Lindsey Guerin
Studies by Andrew Glazer, PhD, Giovanni Davogustto, MD, and colleagues found that genetic testing with information from electronic health records can reveal undiagnosed heart rhythm disorders.
April 28, 2022

Studies combine genetic testing, electronic health records to find undiagnosed diseases

Combining genetic testing with information from electronic health records revealed undiagnosed heart rhythm disorders and new conditions associated with inherited cancer gene mutations.

By Leigh MacMillan
September 17, 2021

Grant creates center for maternal, pediatric precision therapeutics

Vanderbilt University Medical Center has been awarded a five-year, $6 million grant from the National Institutes of Health to serve as a center of excellence for Maternal and Pediatric Precision in Therapeutics.

By Christina Echegaray
September 2, 2021

Study shows gene-drug interactions are common

When a drug or combination of drugs causes different responses in different people, genetic variation is often at play. Pharmacogenomics, through discovery of genetic risk and use of clinical genotyping, aims to reduce trial-and-error approaches to drug prescribing.

By Paul Govern
From left, Dan Roden, MD, Ayesha Muhammad, Jonathan Mosley, MD, PhD, and Sara Van Driest, MD, PhD, found that a genome-wide approach can improve the prediction of drug responses.
July 22, 2021

For more precise drug treatments, ‘squeeze’ the genome: study finds

Large-scale studies will be required to identify the complexity of genetic variations that affect how patients respond to a given drug and whether they will have side effects, according to researchers at Vanderbilt University Medical Center.

By Bill Snyder
April 5, 2021

Codeine metabolizer status in clinical practice

Vanderbilt researchers have developed a response score using genetic and clinical information to aid prescribing of the widely used pain medication codeine.
By Leigh MacMillan
March 15, 2021

Roden honored with Oscar B. Hunter Career Award in Therapeutics

Dan Roden, MD, Senior Vice President for Personalized Medicine at Vanderbilt University Medical Center, received the Oscar B. Hunter Career Award in Therapeutics last week at the virtual annual meeting of the American Society for Clinical Pharmacology and Therapeutics.
By Leigh MacMillan
April 30, 2020

PREDICT program expands, opens new Genomics Clinic

A new clinic opening at Vanderbilt University Medical Center will help doctors and patients choose the best drugs for their medical conditions based on the patients’ unique genetic makeup.
By Bill Snyder
November 6, 2019

Study finds acid reducers may pose risk for children

The use of acid reducers among children is on the rise and so are potential side effects, which is sparking concern according to a recent study.
By Jessica Pasley
January 25, 2018

Personalized drug prescribing program expands, upgrades

Vanderbilt University Medical Center (VUMC) has expanded and relaunched genetic testing to predict patient responses to drugs.
By Paul Govern
March 31, 2016

Study looks at doctors’ response to genetic testing

A new clinical implementation study from Vanderbilt University Medical Center measures how physicians have responded to the introduction of routine genetic testing to predict patient response to the commonly prescribed antiplatelet drug clopidogrel.
By Paul Govern
July 9, 2015

VUMC lands major pharmacogenomics grant

Vanderbilt University Medical Center has received a five-year, $12.8 million grant from the federal government to develop better ways to predict how patients will respond to the drugs they’re given.
By Bill Snyder
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