Infectious Diseases

Coronavirus pioneer Mark Denison bids farewell to VUMC colleagues after remarkable career

The discoveries about coronavirus biology that Denison and his colleagues made were foundational for the rapid validation of antiviral drugs and development of new vaccines that helped bring the COVID-19 pandemic under control.

VUMC infectious disease experts explain what antibiotic resistance means for individuals and populations — and how to protect against it

A rising global health threat, antibiotic resistance presents several complications, but protection is possible.

$4.1 million grant awarded to study unnecessary antibiotic prescriptions 

Antibiotic prescriptions handed out in unplanned care spaces contribute to antimicrobial resistance, especially if they are not necessary to treat infections.

A link between bacterial infection and colorectal cancer: study

Understanding factors that contribute to the development of colorectal cancer could point to new targets for treating the disease at earlier stages, when survival rates are highest.

C. diff uses toxic compound to fuel growth advantage

The findings of a new research study increase understanding of the molecular drivers of C. diff infection and point to novel therapeutic strategies aimed at a pathogen that causes about half a million infections in the U.S. each year.

VUMC to develop AI technology for therapeutic antibody discovery

The approach will address “bottlenecks” that slow the traditional antibody discovery process, and it aims to make it possible to generate monoclonal antibody therapies against any target of interest.

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