Alzheimer’s disease Archive — Page 3 of 8

Stylized axial brain scan illustration in blue, white, and gray, overlaid with radiology-style grid markers, orientation labels, measurement scales, and timestamp-like text.
June 12, 2023

Images predict functional decline

MRI brain scans at baseline for study participants 60 and older — who were free of clinical dementia at study entry — predicted a decline in independent function five years later.

Multiple sagittal brain MRI scans arranged in a radiology film layout, with small technical labels throughout.
May 22, 2023

Neurofluid flow and Alzheimer’s disease

Vanderbilt researchers used novel MRI methods to noninvasively quantify measures of neurofluid circulation and found that hypertrophy of a site of cerebrospinal fluid egress may be related to amyloid-beta retention in Alzheimer’s disease.

Stylized blue profile of a human face formed from a wireframe grid, merging with glowing circuit-board traces and digital data patterns.
May 9, 2023

Neural networks probe proteins

A machine learning method based on neural networks outperformed a mutational scanning model at identifying disease-causing mutations in an Alzheimer’s disease protein, suggesting the method could be useful for facilitating therapeutic design.

Blue side profile of a human head silhouette containing interlocking colorful gears, symbolizing brain function and the workings of the human body.
November 8, 2022

Alzheimer’s risk factor and cognition

Vanderbilt researchers found that a protein with roles in innate immunity worsens memory at baseline in carriers of APOE-e4, the strongest genetic risk factor for Alzheimer’s disease, further implicating neuroinflammation in cognitive decline.

Networked dots in the shape of a brain
October 3, 2022

Minority patients less likely to have amyloid plaques necessary for Alzheimer’s treatments

Fewer Black, Hispanic and Asian patients meet biomarker qualifications for landmark treatments that may slow the progression of Alzheimer’s disease by targeting amyloid plaques, according to new findings published in JAMA Neurology.

Former patient Herbert Christopher poses for a photo with Elizabeth Perkins, MD, the first Christopher fellow of Otolaryngology.
September 15, 2022

Gifts bolster otolaryngology, Alzheimer’s disease programs

Herbert Christopher, a grateful Otolaryngology–Head and Neck Surgery patient who received cochlear hearing implants from David Haynes, MD, has funded the training of otolaryngology fellows and leaders in Alzheimer’s disease care through several outright endowed gifts and additional gift planning with his estate.