Alzheimer’s disease Archives
Grant supports research on abnormal brain aging
Aug. 6, 2020—With the aid of an $18.2 million, five-year grant renewal from the National Institute on Aging, the Vanderbilt Memory and Aging Project (VMAP) will advance interdisciplinary research into abnormal brain aging and cognitive decline in older adults, with continuing emphasis on the role of blood flow changes in the heart and brain.
New study examines Alzheimer’s disease images and molecular biomarkers
May. 7, 2020—Alzheimer’s disease (AD) involves distinctive wasting away of certain brain regions, such that medical imaging of these regions can distinguish the disease from other subtypes of dementia.
Study seeks link between menopause, Alzheimer’s
Feb. 12, 2020—Beginning this month, researchers from VUMC and the University of Vermont are launching a study to examine whether cognitive changes that occur at menopause for some women are related to an increased risk for Alzheimer's disease.
Study examines HIV drug’s potential to treat Alzheimer’s
Dec. 12, 2019—A drug used to treat and prevent HIV/AIDS is showing promise as a potential therapy for Alzheimer’s disease.
Study reveals mysteries of critical brain receptor complex
Dec. 5, 2019—Poorly functioning AMPARs have been linked to a wide range of neurological and psychiatric disorders including seizures, Alzheimer’s disease, major depression and autism spectrum disorder. Understanding how AMPARs are formed and operate is essential for the rational design of pharmacological compounds that, by tuning AMPAR activity up or down, could improve treatment of these conditions.
Grant bolsters Schrag’s Alzheimer’s disease research
Oct. 17, 2019—Matthew Schrag, MD, PhD, assistant professor of Neurology, has received a Paul B. Beeson Emerging Leaders Career Development Award in Aging for research into the function of a novel protein linked to Alzheimer’s disease risk.
Study examines pain processing in co-occurring cancer, Alzheimer’s disease
Oct. 10, 2019—A new multisite study will examine whether co-occurring Alzheimer’s disease and stage 4 breast or prostate cancer alters pain perception, potentially leading to undertreated cancer pain.
Vitamin C protects brain from seizures
Nov. 8, 2018—Brain ascorbate — vitamin C — is important for protecting the brain against seizures and cognitive decline in Alzheimer’s disease.
Probing the pathology of impaired cognition
Oct. 25, 2018—Detecting the neuropathology underlying cognitive impairment by lead to new targeted therapies.
Study links aortic stiffness with lower cerebral blood flow
Aug. 30, 2018—Greater aortic stiffness is related to lower cerebral blood flow, especially among individuals with increased genetic predisposition to Alzheimer’s disease, according to research from Vanderbilt University Medical Center.
Study provides robust evidence of sex differences with Alzheimer’s gene
May. 7, 2018—The APOE gene, the strongest genetic risk factor for Alzheimer’s disease, may play a more prominent role in disease development among women than men, according to new research from the Vanderbilt Memory and Alzheimer’s Center.
Alzheimer’s proteins in ICU survivors
Mar. 27, 2018—The cognitive impairment that affects patients who survive a stay in the ICU does not appear to have a similar mechanism to Alzheimer’s disease, Vanderbilt researchers have discovered.
