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Alzheimer’s disease Archives

Study provides robust evidence of sex differences with Alzheimer’s gene

May. 7, 2018—The APOE gene, the strongest genetic risk factor for Alzheimer’s disease, may play a more prominent role in disease development among women than men, according to new research from the Vanderbilt Memory and Alzheimer’s Center.

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Alzheimer’s proteins in ICU survivors

Mar. 27, 2018—The cognitive impairment that affects patients who survive a stay in the ICU does not appear to have a similar mechanism to Alzheimer’s disease, Vanderbilt researchers have discovered.

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Vitamin C deficiency and mitochondrial dysfunction in Alzheimer’s disease

Dec. 1, 2017—Recent findings suggest that vitamin C deficiency could contribute to Alzheimer’s disease, suggesting that avoiding deficiency through diet and supplementation could protect against disease onset.

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Research links heart function to brain’s memory center

Nov. 8, 2017—Research by a team of Vanderbilt University Medical Center (VUMC) scientists suggests that older people whose hearts pump less blood have blood flow reductions in the temporal lobe regions of the brain, where Alzheimer’s pathology first begins.

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Gender, pain and dementia

Oct. 16, 2017—Understanding sex differences in pain perception could lead to more targeted and effective pain assessment and management strategies in older adults with Alzheimer’s disease.

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Pain and Alzheimer’s disease

Sep. 5, 2017—Clinicians should use a structured interview in people with Alzheimer’s disease to identify pain that might be otherwise overlooked.

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Protein structure may aid in treating Alzheimer’s disease

Apr. 27, 2017—A new protein structure may guide the development of Alzheimer's therapeutics.

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Dementia linked to diet

Feb. 7, 2017—Some memory deficits observed in Alzheimer’s disease may be due to co-morbid illnesses – not the disease itself – and may be reversed by lifestyle changes or pharmacologic interventions.

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Learn about Alzheimer’s disease and dementia research at public forum

Jan. 25, 2017—Vanderbilt researchers will discuss their groundbreaking studies on Alzheimer’s disease and dementia at an upcoming forum, and the public is invited to attend.

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Investigational new drug for Alzheimer’s scheduled for first study in humans

Dec. 27, 2016—Vanderbilt University scientists have received notification from the U.S. Food and Drug Administration that testing in humans may proceed for an investigational new drug for Alzheimer's disease after more than 10 years of research by scientists at Vanderbilt University and Vanderbilt University Medical Center.

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Alzheimer’s study establishes way to measure resilience

Nov. 10, 2016—Vanderbilt researchers have established a new measure of resilience to cognitive impairment in people with asymptomatic Alzheimer’s disease.

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Vanderbilt study shows people with Alzheimer’s have lower ability to perceive pain

Jul. 12, 2016—People with Alzheimer’s disease don’t perceive pain as readily as healthy older adults, and this may lead to delays and underreporting of pain. This alteration in pain detection may be one reason that people with Alzheimer’s disease and pain tend to be undermedicated and suffer unnecessarily, a trans-institutional group of Vanderbilt researchers reported recently in BMC Medicine.

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