A drug used to treat and prevent HIV/AIDS is showing promise as a potential therapy for Alzheimer’s disease.

Poorly functioning AMPARs have been linked to a wide range of neurological and psychiatric disorders including seizures, Alzheimer’s disease, major depression and autism spectrum disorder. Understanding how AMPARs are formed and operate is essential for the rational design of pharmacological compounds that, by tuning AMPAR activity up or down, could improve treatment of these conditions.

Matthew Schrag, MD, PhD, assistant professor of Neurology, has received a Paul B. Beeson Emerging Leaders Career Development Award in Aging for research into the function of a novel protein linked to Alzheimer’s disease risk.

A new multisite study will examine whether co-occurring Alzheimer’s disease and stage 4 breast or prostate cancer alters pain perception, potentially leading to undertreated cancer pain.

The ways certain proteins spread may help explain why the prevalence of Alzheimer’s is higher in women than in men.

A neurologist is using a mapping analysis in a new study to rethink where symptoms or cognitive processes should show up in the brain. The results are ‘powerful.’

Brain ascorbate — vitamin C — is important for protecting the brain against seizures and cognitive decline in Alzheimer’s disease.