autoimmune disease
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May 5, 2022
COVID-associated bleeding risk
While case reports have noted acquired hemophilia after COVID-19 infection or vaccination, a new study finds no increased risk. -
January 27, 2022
Impaired neutrophils in autoimmunity
Vanderbilt researchers help answer the question of why patients with autoimmune diseases like lupus are more susceptible to bacterial infections: their neutrophils have impaired antibacterial activity. -
September 16, 2021
‘Pre-conditioning’ restores immune tolerance
A treatment targeting T-cell metabolism could reinvigorate immune tolerance mechanisms to combat autoimmune disease and transplant rejection, Vanderbilt researchers discovered. -
August 24, 2021
Autoimmunity advance
Vanderbilt researchers have developed a high-throughput screening method to identify and characterize antigen-specific B cells — potential biomarkers for autoimmune disease and targets for new treatments. -
March 25, 2021
Team studies new use for pulmonary hypertension drug
An FDA-approved medication enhances the function of T regulatory cells (Treg), a class of immune cells that restrains the immune response, Vanderbilt investigators have discovered. -
July 13, 2020
“Nur” target may aid arthritis treatment
Vanderbilt immunologists have discovered that the protein Nur77 is part of a control mechanism that guards against autoimmunity in natural killer T cells. -
May 19, 2020
Probing innate immunity
Manuel Ascano team validates an inhibitor of the cGAS-STING signaling pathway, which is important for cellular innate immunity against bacteria, viruses, and our own damaged DNA.