BioVU

April 24, 2019

Study merges big data and zebrafish biology to reveal mechanisms of human disease

In a series of studies that volleyed between large databases and research in zebrafish, Vanderbilt investigators have discovered a link between vascular biology and eye disease.

By Leigh MacMillan
Lisa Bastarache, MS, Josh Denny, MD, MS, and colleagues are helping researchers study associations among de-identified genotype data and electronic health records data. (photo by John Russell)
February 7, 2019

PheWAS Core helps researchers make sense of electronic health record data

Some biomedical researchers may be unsure about routine electronic health record (EHR) data and how useful it ultimately may prove for drawing meaningful, actionable associations that warrant changes to clinical practice and lead to improved clinical outcomes.

By Paul Govern
January 31, 2019

Study explores genetic risk for suicide attempt

Using data from the UK Biobank and Vanderbilt’s BioVU, a new study in the journal Molecular Psychiatry finds that approximately 4 percent of suicide attempt risk is captured by genotype data.

By Paul Govern
December 31, 2018

Hundreds of new blood pressure gene variations discovered

By Bill Snyder
October 25, 2018

Grant to help explore critical issues in Down syndrome

The Vanderbilt Kennedy Center (VKC) has received a one-year $604,000 grant from the National Institute of Child Health and Human Development (NICHD) to use Vanderbilt University Medical Center electronic medical record information and biological samples to develop a deeper understanding of critical issues in Down syndrome and to provide an infrastructure for future analyses.

By Jan Rosemergy
October 15, 2018

Malin elected to National Academy of Medicine

Bradley Malin, PhD, professor of Biomedical Informatics, Biostatistics and Computer Science, is among 85 newly elected members of the National Academy of Medicine (NAM), the organization announced this week.

By Paul Govern
September 20, 2018

Fibromyalgia: More doctor visits mean fewer suicide attempts

Fibromyalgia patients who regularly visit their physicians are much less likely to attempt suicide than those who do not, according to a new Vanderbilt University Medical Center study published in Arthritis Care & Research.
By Craig Boerner
April 19, 2018

VUMC drug repurposing initiative gaining momentum

Drug repurposing involves establishing an additional approved indication for a drug already at market.
By Paul Govern
April 5, 2018

Nashville Biosciences created to leverage wealth of data

Officials with Vanderbilt University Medical Center announced the creation of a wholly owned subsidiary, Nashville Biosciences, to harness the power of its extensive genomic and bioinformatics resources to advance drug and diagnostics discovery and development.
By Bill Snyder
March 22, 2018

Grant bolsters study of potential new therapy for C. diff infection

According to the Centers for Disease Control and Prevention, in 2011 in the United States there were almost half a million Clostridium difficile infections, and one in 11 patients 65 or older with a healthcare-associated C. diff infection died within 30 days of diagnosis.
By Paul Govern
March 15, 2018

Study spots undiagnosed genetic diseases in EHR

Patients diagnosed with heart failure, stroke, infertility and kidney failure could actually be suffering from rare and undiagnosed genetic diseases.
By Craig Boerner
February 26, 2018

Cannabis compound reduces seizures

Cannabidiol (CBD) oils reduced seizures in patients with difficult-to-treat epilepsy, Vanderbilt investigators have found.
By Leigh MacMillan
November 16, 2017

Study may point to new treatment approach for ASD

Using sophisticated genome mining and gene manipulation techniques, researchers at Vanderbilt University Medical Center (VUMC) have solved a mystery that could lead to a new treatment approach for autism spectrum disorder (ASD).
By Bill Snyder