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breast cancer Archives

Surgery for hereditary breast cancer

Nov. 17, 2022—Similar rates of bilateral mastectomy in women with inherited mutations in high- and moderate-penetrance genes raises concerns about possible overtreatment of some patients, Vanderbilt researchers report.

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Cell-free breast cancer “biopsy”

Aug. 11, 2022—The circulating DNA that tumors release is a reliable metric of tumor genomics and can be used to monitor molecular changes in metastatic breast cancer.

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Five-year, multi-site trial to assess lymphedema prevention concludes

Jun. 20, 2022—Lymphedema study results could be a game-changer for breast cancer patients and survivors. The Vanderbilt-led trial found that patients with early detection who used L-Dex with additional intervention were less likely to progress to chronic lymphedema than patients monitored with a tape measure receiving the same intervention. 

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Breast cancer biomarkers of response

Jun. 16, 2022—Vanderbilt researchers have identified blood-based biomarkers associated with complete responses to neoadjuvant chemotherapy in patients with breast cancer.

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New Clinician Spotlight: Kelly Hewitt

Dec. 8, 2021—Kelly Hewitt, MD, recently joined the Division of Surgical Oncology after being recruited from St. Charles Health System in Bend, Oregon, where she served as medical director of the Breast Program.

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‘Multi-omics’ reveals treatment option for breast cancer subtype

Nov. 18, 2021—  by Bill Snyder In a multidisciplinary collaboration, researchers at Vanderbilt University Medical Center and the University of Miami Miller School of Medicine have identified a subtype of triple-negative breast cancer (TNBC) that appears to be able to escape detection by the immune system and evade immunotherapy. Their report, published Nov. 1 in the journal...

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Breast cancer survivors: eat nuts

Nov. 1, 2021—Breast cancer survivors who reported eating nuts regularly had 50% reduced risk of breast cancer recurrence, metastasis or mortality, Vanderbilt epidemiologists found in Shanghai Breast Cancer Survival Study.

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Study shows how a protein coding gene confers breast cancer susceptibility during DNA transcription

Sep. 30, 2021—Vanderbilt-Ingram Cancer Center research is providing new insights into how genetic variants convey breast cancer susceptibility by altering the transcription factor proteins that convert DNA strands into RNA.

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Structural variants in breast cancer risk genes

Sep. 16, 2021—Vanderbilt epidemiologists conducted in-depth whole genome sequencing of breast cancer risk genes in Black women, who die at higher rates and have more aggressive disease, to discover mutations that may improve testing and treatment selection.

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Study identifies biomarker for breast cancer response to immunotherapy

Aug. 12, 2021—A biomarker that has proven to be a predictor for response to immunotherapies in melanoma patients also has clinical relevance for breast cancer patients, according to a new study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

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Prediction models for breast cancer

Jul. 27, 2021—Vanderbilt researchers developed new prognostic models for breast cancer outcomes and found that adding postdiagnostic weight change as a factor improves the prediction.

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Mood and cognition after chemotherapy

Jul. 26, 2021—Validation of cognitive complaints appears to improve mood in patients with persistent chemotherapy-cognitive impairment, Vanderbilt researchers report.

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