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breast cancer Archives

Breast cancer treatment in older women

Nov. 12, 2020—A new study from Vanderbilt epidemiologists suggests that it’s time to reconsider clinical practice guidelines for the treatment of early-stage breast cancer in older women.

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Screening younger women for hereditary cancers may be cost effective

Nov. 5, 2020—Population-wide screening for genetic variants linked to hereditary breast and ovarian cancer may be cost effective in women between the ages of 20 and 35, according to a study published in JAMA Network Open.

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The importance of estrogen cycles

Aug. 6, 2020—Deborah Lannigan and colleagues identify a key regulator of the estrogen receptor and suggest that its downregulation by oral contraceptives may increase oxidative stress and DNA damage, a common cause of cancer.

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Triple-negative breast cancer drug therapy shows promise

Mar. 12, 2020—Researchers from Vanderbilt-Ingram Cancer Center (VICC) discovered a role for MYCN in triple-negative breast cancer (TNBC), a particularly aggressive form of the disease, and identified a potential intervention for further clinical investigation.

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Breast cancer study may help predict treatment response

Feb. 27, 2020—Researchers at VUMC are reporting another advance in the understanding and treatment of triple-negative breast cancer, which is particularly aggressive and difficult to treat.

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Imaging breast cancer cell size

Feb. 10, 2020—A noninvasive MRI approach assesses breast tumor cell size and could be a useful way to evaluate early response to neoadjuvant therapy.

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HDL-cholesterol and breast cancer risk

Jan. 23, 2020—Genetic analyses suggest that high circulating HDL-cholesterol levels may increase breast cancer risk — a surprising finding since increased HDL-cholesterol is thought to be healthy.

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ACMG issues statement on breast cancer genetic testing

Jan. 16, 2020—According to a statement on behalf of the American College of Medical Genetics and Genomics, there is insufficient evidence to recommend universal genetic testing for BRCA1/2 alone or in combination with multi-gene panels for all breast cancer patients.

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The American College of Medical Genetics and Genomics advises evaluating all breast cancer patients to determine the need for genetic testing

Dec. 13, 2019—According to a statement on behalf of the American College of Medical Genetics and Genomics, there is insufficient evidence to recommend universal genetic testing for BRCA1/2 alone or in combination with multi-gene panels for all breast cancer patients.

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Study finds breast cancer recurrence score has different implications for men

Nov. 20, 2019—A study published last year offered good news for women with early-stage ER-positive breast cancer who scored at intermediate risk for recurrence. However, a new study finds this conclusion may not directly apply to male patients with the same type of breast cancer

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Breast cancer research pioneer Page remembered

Oct. 24, 2019—David Page, MD, former professor of Pathology and Preventive Medicine at Vanderbilt University School of Medicine, whose work revolutionized the assessment of breast cancer risk, died in Nashville on Thursday, Oct. 17. He was 78.

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Pietenpol, Wilson land Komen cancer research support

Oct. 24, 2019—Two Vanderbilt-Ingram Cancer Center investigators have received financial support from Susan G. Komen for breast cancer research.

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