Circulation (journal)

April 30, 2024

Atherosclerosis is a tumor-like disease: study

An anticancer drug blunted atherosclerosis progression — and even made plaques shrink — in a mouse model of the disease, opening new opportunities for preventing and treating this leading cause of death.

By Leigh MacMillan
The study could suggest ways to promote the transport of phospholipids and cholesterol out of macrophages, immune system cells that play key roles in all stages of atherosclerosis development.
March 23, 2023

Reminders for clinicians improve prescribing for high cholesterol

A Vanderbilt study found that automated targeted reminders for clinicians helped increase prescribing of high intensity statins for patients with various atherosclerotic cardiovascular disease diagnoses, including coronary or peripheral artery disease and ischemic stroke.

By Paul Govern
February 23, 2023

Study sheds new light on hormone therapy as menopause treatment

Vanderbilt research shows that hormone replacement therapy can be safely administered depending on the method used and the patient’s age, time since menopause, and risk of cardiovascular disease.

By Matt Batcheldor
The research team included, from left, Hannah Poisner, Sydney Olson, J. Brett Heimlich, MD, PhD, Ningning Hu, MS, Alyssa Parker, Alexander Bick, MD, PhD, Joseph Van Amburg and Tara Mack.
February 2, 2023

Researchers clarify role of blood cell mutations in disease

Vanderbilt researchers have developed a new method to analyze mutations in blood stem cells that can trigger explosive, clonal expansions of abnormal cells.

By Bill Snyder
December 15, 2022

Reduced kidney function may cause cardiovascular disease: study

An international team of investigators has found that mild to moderate reduction in kidney function may cause cardiovascular disease, even in people without symptoms of heart disease or diabetes.

By Bill Snyder
Studies by Andrew Glazer, PhD, Giovanni Davogustto, MD, and colleagues found that genetic testing with information from electronic health records can reveal undiagnosed heart rhythm disorders.
April 28, 2022

Studies combine genetic testing, electronic health records to find undiagnosed diseases

Combining genetic testing with information from electronic health records revealed undiagnosed heart rhythm disorders and new conditions associated with inherited cancer gene mutations.

By Leigh MacMillan
February 24, 2022

VUMC researchers find clue to drug-induced arrhythmias

Vanderbilt University Medical Center researchers have made a fundamental discovery about how the heart compensates for genetic variations that otherwise could trigger abnormal and potentially fatal heart rhythms.
By Bill Snyder
February 21, 2019

AHA statement supports vascular cardio-oncology

The American Heart Association (AHA) has issued a scientific statement calling for the integration of cardio-oncology and vascular medicine to provide cancer patients and cancer survivors with optimal cardiovascular care.
By Tom Wilemon
August 30, 2018

Study links aortic stiffness with lower cerebral blood flow

Greater aortic stiffness is related to lower cerebral blood flow, especially among individuals with increased genetic predisposition to Alzheimer’s disease, according to research from Vanderbilt University Medical Center.
By Tom Wilemon
May 3, 2018

Gene study spots clues to heart risk for statin patients

A Vanderbilt-led research team has discovered genetic variations that increase the risk of heart attack even when patients are receiving a statin drug like Lipitor or Crestor to lower their blood cholesterol.
By Bill Snyder
April 5, 2018

Report calls for greater awareness of rare cardiac disease

A national effort seeks to raise awareness about an uncommon cause of heart attacks in otherwise healthy, young and middle-aged women.
By Jessica Pasley
May 17, 2016

Study finds menthol cigarettes do not further increase smokers’ cardiovascular disease, stroke risk

Smoking is deleterious to health, but smokers who prefer menthol cigarettes to nonmenthol can breathe a sigh of relief…for now.
By Kathy Whitney
February 4, 2016

Prostate cancer survivors’ risk of heart disease studied

The 3 million prostate cancer survivors in the United States are likely to die from something other than cancer, thanks to early detection, effective treatment and the disease’s slow progression.
By Kathy Whitney
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