Circulation (journal) Archive — Page 1 of 2

May 11, 2026

Multi-organ metabolite ‘signature’ signals increased heart failure risk

A multi-institutional group has identified a “signature” of metabolic molecules associated with exercise-induced physiologic deficits that, when released into the bloodstream, signal heightened heart failure risk.

By Bill Snyder
April 30, 2024

Atherosclerosis is a tumor-like disease: study

An anticancer drug blunted atherosclerosis progression — and even made plaques shrink — in a mouse model of the disease, opening new opportunities for preventing and treating this leading cause of death.

By Leigh MacMillan
The study could suggest ways to promote the transport of phospholipids and cholesterol out of macrophages, immune system cells that play key roles in all stages of atherosclerosis development.
March 23, 2023

Reminders for clinicians improve prescribing for high cholesterol

A Vanderbilt study found that automated targeted reminders for clinicians helped increase prescribing of high intensity statins for patients with various atherosclerotic cardiovascular disease diagnoses, including coronary or peripheral artery disease and ischemic stroke.

By Paul Govern
February 23, 2023

Study sheds new light on hormone therapy as menopause treatment

Vanderbilt research shows that hormone replacement therapy can be safely administered depending on the method used and the patient’s age, time since menopause, and risk of cardiovascular disease.

By Matt Batcheldor
The research team included, from left, Hannah Poisner, Sydney Olson, J. Brett Heimlich, MD, PhD, Ningning Hu, MS, Alyssa Parker, Alexander Bick, MD, PhD, Joseph Van Amburg and Tara Mack.
February 2, 2023

Researchers clarify role of blood cell mutations in disease

Vanderbilt researchers have developed a new method to analyze mutations in blood stem cells that can trigger explosive, clonal expansions of abnormal cells.

By Bill Snyder
December 15, 2022

Reduced kidney function may cause cardiovascular disease: study

An international team of investigators has found that mild to moderate reduction in kidney function may cause cardiovascular disease, even in people without symptoms of heart disease or diabetes.

By Bill Snyder