colon and rectal (colorectal) cancer

September 12, 2023

Study finds new genetic susceptibilities for colon cancer

Vanderbilt researchers at have found new genes that put people at higher risk for colon cancer and rectal cancer. 

By Tom Wilemon
July 19, 2023

Holowatyj receives National Cancer Institute MERIT Award

Vanderbilt’s Andreana Holowatyj, PhD, MSCI, has received the National Cancer Institute’s Method to Extend Research in Time Award to support her ongoing investigation into how early-onset colorectal cancer and its treatments impact reproductive health.

By Tom Wilemon
June 29, 2023

Selenium signal found in colorectal cancer: study

An antioxidant transporter of the trace mineral selenium that protects against inflammatory bowel disease has the opposite effect in colorectal cancer, where it promotes tumor growth, researchers at Vanderbilt University Medical Center have reported.

By Bill Snyder
June 15, 2023

New treatment option for metastatic colorectal cancer prolongs survival

Research conducted at Vanderbilt points to a new therapy is on the horizon for patients with metastatic colorectal cancer who have run out of treatment options.

By Tom Wilemon
May 4, 2023

Better adenoma detection

Fluorescent nanoparticles clearly identified colonic adenomas — precursors to colorectal cancer — in mice, and the formulation should translate to clinical use in humans.

By Sarah E. Glass
September 13, 2022

Patients had ‘significant and clinically meaningful improvement’ in survival in fruquintinib clinical trial

Patients with metastatic colorectal cancer who had not responded to other treatments had “significant and clinically meaningful improvement” in overall survival when treated with the oral targeted therapy fruquintinib.

By Tom Wilemon
August 17, 2022

Trial for colorectal cancer drug reaches primary endpoint

A new therapy for metastatic colorectal cancer that has been granted fast track designation by the U.S. Food and Drug Administration has met its primary endpoint of overall survival in a phase 3 clinical trial.
By Tom Wilemon
July 28, 2022

C. difficile may contribute to colorectal cancer: study

A Vanderbilt study found that the bacterium Clostridioides difficile (C. difficile) may be a previously unrecognized contributor to colorectal cancer.
By Bill Snyder
July 21, 2022

Researchers find potential new target against colorectal cancer

By Bill Snyder
July 12, 2022

Probing the tumor microenvironment

Vanderbilt researchers used single-cell sequencing, imaging, and computational approaches to characterize the colonic tumor microenvironment, providing important insights to the components that play roles in colorectal tumor pathogenesis.
By Leigh MacMillan
June 2, 2022

Choi, Short receive AGA Research Foundation Awards

Two Vanderbilt researchers have received awards from the AGA Foundation, the charitable arm of the American Gastroenterological Association.
By Tom Wilemon
May 6, 2022

Janet Darnell received a lifesaving lung transplant. Five months later she received lifesaving surgery for colon cancer. She calls herself a “walking miracle.”

Without the lung transplant, the cancer may never have been detected.
By Matt Batcheldor
March 9, 2022

Martin shares colorectal cancer story, urges early detection

Vanderbilt Wilson County Hospital's Lori Martin uses her own experiences to educate patients about the importance of early detection of colorectal cancer.
By Tom Wilemon
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