Department of Anesthesiology

Protocol helps manage blood glucose during surgery

A study conducted by researchers in the Department of Anesthesiology found a clinical information systems protocol, developed by the department’s Vanderbilt Perioperative Information Management Systems (VPIMS) developer group, improved management of blood glucose during the intraoperative period, resulting in reduced instances of hyperglycemia as well as a reduction in surgical site infections in diabetic patients and those with impaired glucose control following surgical procedures.

Laughing gas for labor

Although nitrous oxide was less effective than epidural anesthesia for pain management during labor, mothers who used nitrous oxide were equally satisfied with their childbirth experience.

Pathology of septic shock

The signaling molecule IL-15 promotes septic shock, a life-threatening condition involving organ injury caused by infection.

Improving vaccine formulations

The compound MPLA is an attractive vaccine component, designed to elicit a robust immune response.

Investigators explore new way to control mosquitoes

In a new study, Vanderbilt pharmacologist Jerod Denton, Ph.D., Ohio State entomologist Peter Piermarini, Ph.D., and colleagues report an experimental molecule that inhibits kidney function in mosquitoes and thus might provide a new way to control the deadliest animal on Earth.

Probing drug abuse circuitry

Vanderbilt researchers have identified cocaine-induced modifications at specific neuronal connections, which could aid the development of new therapies for substance abuse disorders.

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