Department of Cell and Developmental Biology

Grant funds quest to expand immunotherapy efficacy for colorectal cancer  

The study seeks to understand the mechanisms of colorectal cancer and builds on recent Vanderbilt research.

(Adobe Stock)

Study finds human milk component may protect adult intestinal health

The research may lead to new treatments for diseases such as inflammatory bowel disease and mucositis, a severe complication of chemotherapy.

2024 Chancellor Faculty Fellows selected

Each fellow holds the title for two years, receives $40,000 per year to support their work, and meets with their cohort to exchange ideas, build a broader intellectual community and engage in academic leadership development.

Eunyoung Choi, PhD, and James Goldenring, MD, PhD. (photo by Erin O. Smith)

Grant funds research for therapies to prevent stomach cancer

The funds will help launch a clinical trial in the U.S. with one of the therapies and compare it with another therapy from an ongoing clinical trial in Japan.

Ken Lau, PhD, left, and Bob Coffey, MD, have made several important discoveries about colorectal cancer that are aiding the search for new, more effective therapies. (photo by Erin O. Smith)

Colorectal cancer ‘cartography’ reveals an avenue to improved immunotherapy

Vanderbilt University Medical Center researchers have discovered why most colorectal tumors escape detection and destruction by the body’s immune system.

A C. diff bacterium (green) with iron particles in red, shown in a reconstructed electron tomogram from STEM-EDS. (image courtesy of James McBride)

Novel C. diff structures are required for infection, offer new therapeutic targets

Vanderbilt research discovers that iron storage “spheres” inside the bacterium C. diff — the leading cause of hospital-acquired infections — are important for infection in an animal model and could offer new targets for antibacterial drugs.

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