Department of Medicine

The combination of genomics and metabolism identified a long-sought mitochondrial choline transporter.

Department of Medicine clinicians see patients in 19 counties across Middle Tennessee as well as the surrounding region. There were 86,096 outpatient visits for fiscal year 2024, an increase of more than 25,000 visits over fiscal year 2023.

The therapy, haploidentical bone marrow transplant with thiotepa and posttransplant cyclophosphamide, is as safe and more affordable than the recently FDA-approved myeloablative gene therapy and gene editing treatments.

The study was the largest ancestry-stratified, genetic estimation of the heritability of diabetic retinopathy conducted to date and included an unprecedented number of individuals of non-Hispanic African ancestry — more than 46,000.

This new entry to the field works in the background to provide real-time risk assessments, with no manual inputs from health care providers required.

The authors hope the report will provide insight on the importance of education, screening and awareness to all health care providers.

The Vanderbilt study used RNA-sequencing data generated in multiple normal tissues, along with matched genotype data from the Genotype-Tissue Expression Project as well as large-scale genomic data for cancers of the breast, ovary, prostate, colorectum, lung and pancreas.