Department of Medicine

From left, Simon Mallal, MBBS, and John Koethe, MD, MSCI. (photo by Susan Urmy)
March 29, 2024

VUMC’s John Koethe named director of the Tennessee Center for AIDS Research

John Koethe, MD, MSCI, associate professor of Medicine in the Division of Infectious Diseases at Vanderbilt University Medical Center, has been appointed director and principal investigator of the Tennessee Center for AIDS Research.

By Bill Snyder
March 28, 2024

Teams to create one-stop resource for human pancreatic data to foster diabetes research

Leading investigators in diabetes, pancreas and islet biology, and computational biology have received $12.5 million in two five-year awards from the National Institutes of Health (NIH) to create the world’s first, integrated knowledge base of human-derived tissue- and cellular-level pancreatic information to support innovative, collaborative and reproducible research.

By Jill Clendening
March 28, 2024

Study identifies molecule as potential target for treating AML

While immune checkpoint inhibitors that target the PD-1 molecule on T-cells have proven to be effective with many cancers, these immunotherapies have not worked for acute myeloid leukemia (AML), but new research has identified a “cousin” molecule as a potential therapeutic target for AML. 

By Tom Wilemon
March 27, 2024

Higher genetic risk of obesity means working out harder for same results 

Study authors used activity, clinical and genetic data from the National Institutes of Health’s All of Us Research Program to explore the association of genetic risk of higher body mass index and the level of physical activity needed to reduce incident obesity. 

By Craig Boerner
March 26, 2024

GRADE Study expands results of major NIH-sponsored comparative study of glucose lowering medications in Type 2 diabetes

The study, which included more than 5,000 volunteers with Type 2 diabetes from diverse racial and ethnic groups, compared the treatments insulin glargine, liraglutide, glimepiride and sitagliptin.
(iStock image)
March 25, 2024

VUMC team finds potential treatment for kidney fibrosis

By Bill Snyder
March 18, 2024

Bariatric surgery linked to cardiometabolic health improvements: study

Bariatric surgery can lead to significant cardiometabolic health improvements using a variety of measures, including blood pressure, cholesterol, glucose and hemoglobin A1C, according to a new study published in the Journal of the Endocrine Society.  
By Jill Clendening
March 18, 2024

VUMC’s Sunil Kripalani joins AHRQ Advisory Council

The Agency for Healthcare Research and Quality Council helps guide national priorities for health services research that promotes improvements in the quality, safety and efficiency of clinical practice.
By Bill Snyder
March 15, 2024

Emerging Infections Program extends, expands disease surveillance research with new grant from the CDC

The Tennessee Emerging Infections Program has been awarded a new five-year grant from the Centers for Disease Control and Prevention to continue infectious disease surveillance research that has been conducted since 1999, and has expanded to include COVID, Mpox and HPV surveillance into oropharyngeal cancers.
By VUMC News and Communications
March 14, 2024

Immune cell profiles may guide flu vaccine timing in pediatric stem cell transplant patients

A new study led by Vanderbilt University Medical Center researchers has identified key immune cell populations that predict how well pediatric hematopoietic stem cell transplant (HCT) recipients will respond to the influenza vaccine.
By Paul Govern
March 14, 2024

Pain medication. Cosmetics. Cleaning supplies. Tennessee Poison Center’s message: lock them away.

TPC’s help hotline —1-800-222-1222 — is staffed by nurses, pharmacists, physicians and board-certified medical toxicologists who are specially trained to assist callers.
By Jessica Pasley
March 11, 2024

School of Medicine in top 10 in NIH funding: survey

Vanderbilt University School of Medicine, which received $527.7 million in direct and indirect NIH grant support in FY23, has been among the top 10 U.S. medical schools in NIH funding for six of the last 10 years.
By Bill Snyder
March 8, 2024

Scalp cooling allows woman to keep hair during chemotherapy

The Food and Drug Administration first granted marketing approval for the DigniCap system for patients with breast cancer in 2015, then in 2017 the FDA expanded the authorization, making it the first cooling cap cleared for use in cancer patients with solid tumors, such as breast cancer, ovarian cancer and colorectal cancer.
By Tom Wilemon
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