While immune checkpoint inhibitors that target the PD-1 molecule on T-cells have proven to be effective with many cancers, these immunotherapies have not worked for acute myeloid leukemia (AML), but new research has identified a “cousin” molecule as a potential therapeutic target for AML. 

Study authors used activity, clinical and genetic data from the National Institutes of Health’s All of Us Research Program to explore the association of genetic risk of higher body mass index and the level of physical activity needed to reduce incident obesity. 

The study, which included more than 5,000 volunteers with Type 2 diabetes from diverse racial and ethnic groups, compared the treatments insulin glargine, liraglutide, glimepiride and sitagliptin.

Bariatric surgery can lead to significant cardiometabolic health improvements using a variety of measures, including blood pressure, cholesterol, glucose and hemoglobin A1C, according to a new study published in the Journal of the Endocrine Society.  

The Agency for Healthcare Research and Quality Council helps guide national priorities for health services research that promotes improvements in the quality, safety and efficiency of clinical practice.

The Tennessee Emerging Infections Program has been awarded a new five-year grant from the Centers for Disease Control and Prevention to continue infectious disease surveillance research that has been conducted since 1999, and has expanded to include COVID, Mpox and HPV surveillance into oropharyngeal cancers.