Study identifies molecule as potential target for treating AML

While immune checkpoint inhibitors that target the PD-1 molecule on T-cells have proven to be effective with many cancers, these immunotherapies have not worked for acute myeloid leukemia (AML), but new research has identified a “cousin” molecule as a potential therapeutic target for AML. 

Higher genetic risk of obesity means working out harder for same results 

Study authors used activity, clinical and genetic data from the National Institutes of Health’s All of Us Research Program to explore the association of genetic risk of higher body mass index and the level of physical activity needed to reduce incident obesity. 

GRADE Study expands results of major NIH-sponsored comparative study of glucose lowering medications in Type 2 diabetes

The study, which included more than 5,000 volunteers with Type 2 diabetes from diverse racial and ethnic groups, compared the treatments insulin glargine, liraglutide, glimepiride and sitagliptin.

VUMC team finds potential treatment for kidney fibrosis

Bariatric surgery linked to cardiometabolic health improvements: study

Bariatric surgery can lead to significant cardiometabolic health improvements using a variety of measures, including blood pressure, cholesterol, glucose and hemoglobin A1C, according to a new study published in the Journal of the Endocrine Society.  

VUMC’s Sunil Kripalani joins AHRQ Advisory Council

The Agency for Healthcare Research and Quality Council helps guide national priorities for health services research that promotes improvements in the quality, safety and efficiency of clinical practice.