Department of Pathology Microbiology and Immunology

RNA processing and antiviral immunity

John Karijolich and colleagues have discovered a link between cellular RNA processing and the innate cellular immune response to viral pathogens.

Discovery could lead to neutralizing West Nile virus

Researchers at Vanderbilt University Medical Center and colleagues have isolated a human monoclonal antibody that can “neutralize” the West Nile virus and potentially prevent a leading cause of viral encephalitis (brain inflammation) in the United States.

Team’s findings show glutamine metabolism affects T cell signaling

The cellular nutrient glutamine launches a metabolic signaling pathway that promotes the function of some immune system T cells and suppresses others, Vanderbilt researchers have discovered.

Rubin receives alumni award from Weill Cornell

Donald Rubin, MD, professor of Medicine and Pathology, Microbiology and Immunology at Vanderbilt, has received the alumni award for special achievement from his alma mater, the Weill Cornell Medical College in New York City.

Asthma’s androgen connection

New findings may explain why the prevalence of asthma is higher in women and suggest that testosterone derivatives may be useful for treating more severe types of asthma.

Study reveals new targets to inhibit pulmonary fibrosis

In a study out this week in Science Translational Medicine, an international team led by researchers at Vanderbilt University Medical Center sheds new light on the cause of pulmonary fibrosis and demonstrates a way to impede the disease in mice.

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