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Department of Pharmacology Archives

Vanderbilt scientists report new modeling of brain signaling

Mar. 7, 2019—The release of neurotransmitters and hormones in the body is tightly controlled by complex protein machinery embedded in cell membranes.

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Gene identified that increases risk of antibiotic reaction

Feb. 28, 2019—Researchers at Vanderbilt University Medical Center and colleagues have identified a gene that increases the risk for a severe and potentially life-threatening reaction to the commonly prescribed antibiotic vancomycin.

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Modulating stress circuits

Feb. 14, 2019—Danny Winder and colleagues demonstrate an interaction between two signaling pathways — and its impact on the activity of neurons that respond to stress.

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American Chemical Society honors Lindsley’s research

Jan. 24, 2019—The year is starting off with a bang for Craig Lindsley, PhD, director of medicinal chemistry in the Vanderbilt Center for Neuroscience Drug Discovery (VCNDD).

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Signals from the “conveyor belt”

Jan. 17, 2019—Vanderbilt researchers propose that cellular signaling pathways are amplified by a “conveyor belt” mechanism that exchanges active and inactive enzymes.

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Vanderbilt study suggests way to prevent rare lung disease

Nov. 15, 2018—Research by Vanderbilt scientists suggests that it may be possible to prevent or even reverse pulmonary arterial hypertension, a rare, progressive disease characterized by narrowing of and high blood pressure in the small arteries of the lungs.

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Four researchers receive Young Investigator Grants

Nov. 15, 2018—Four Vanderbilt University researchers are among 200 recipients of this year’s Young Investigator Grants awarded by the Brain & Behavior Research Foundation to support “innovative ideas for groundbreaking neurobiological research.”

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Novel methods to treat glaucoma

Nov. 8, 2018—Increasing a certain signaling molecule prevents the degeneration of retinal cells that are lost in glaucoma, suggesting a new way to treat this disease.

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Cytokine-cognition connection

Oct. 1, 2018—Targeting the immune system may provide a new avenue for therapeutic intervention in psychiatric diseases characterized by motivational and cognitive deficits.

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Innovative strategies crucial in opioid epidemic response

Sep. 27, 2018—Reining in the nation’s opioid epidemic will require diverse and innovative strategies ranging from drug discovery to “policy translation,” according to speakers at a recent Vanderbilt Faculty Cutting-edge Discovery Lecture.

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Student-invited Pharmacology Forum

Jul. 19, 2018—Graduate students in the Department of Pharmacology hosted the 27th annual Joel G. Hardman Student-Invited Pharmacology Forum and presented the annual “Teacher of the Year” award to Joshua Fessel, MD, PhD.

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Vanderbilt licenses compound to Nashville’s Appello to advance Parkinson’s therapies

Jul. 12, 2018—Vanderbilt University has signed a licensing agreement with Nashville-based start-up Appello Pharmaceuticals, Inc. to advance novel compounds developed by researchers in the Vanderbilt Center for Neuroscience Drug Discovery (VCNDD) for the treatment of Parkinson’s disease.

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