In an observational study by researchers at Vanderbilt University Medical Center, adults with type 2 diabetes who take insulin in addition to the recommended first-line drug therapy, metformin, had a 30 percent higher risk of heart attack, stroke or death when compared to similar patients who instead augment their metformin regimen with a sulfonylurea.

The protein CaMKII acts as a calcium sensor in a positive feedback pathway that enhances glucose-stimulated insulin secretion.

The extracellular matrix that surrounds cells plays a role in the development of insulin resistance.

Knowing when to take a medication — and what to do if a dose is missed — could greatly improve adherence to diabetes medications and glycemic control among adults with type 2 diabetes, according to a Vanderbilt study published in the journal Diabetes Care.

Vanderbilt University scientists have found evidence that the insulin-secreting beta cells of the pancreas, which are either killed or become dysfunctional in the two main forms of diabetes, have the capacity to regenerate.

Vanderbilt researchers describe a new technique for identifying factors that stimulate the proliferation of pancreatic beta cells – factors that might offer therapeutic options for diabetes.

Preschool-aged children require the majority of their waking day to achieve their recommended daily physical activity, a Vanderbilt study published in Obesity found.