Division of Genetic Medicine and Clinical Pharmacology Archive — Page 10 of 12

From left, Dan Roden, MD, Ayesha Muhammad, Jonathan Mosley, MD, PhD, and Sara Van Driest, MD, PhD, found that a genome-wide approach can improve the prediction of drug responses.
July 22, 2021

For more precise drug treatments, ‘squeeze’ the genome: study finds

Large-scale studies will be required to identify the complexity of genetic variations that affect how patients respond to a given drug and whether they will have side effects, according to researchers at Vanderbilt University Medical Center.

Blister pack of pink tablets beside a box labeled “STATIN 40 mg” and “28 Tablets,” with a stethoscope in the background.
July 12, 2021

Probing statin-associated diseases with genetics

Vanderbilt researchers used genetics tools and biobanks with linked electronic health records to explore the associations between statins and noncardiovascular diseases.

Close-up of a high-tech laboratory interface displaying the words “COVID-19” and “VIRUS,” with colorful circuit-like lines and data graphics.
July 8, 2021

Study finds genetic risk factors for severe COVID-19 illness

A massive worldwide collaboration including researchers from Vanderbilt University Medical Center (VUMC) has identified several genetic factors associated with SARS-CoV-2 infection and severe COVID-19 illness.

Multiple blue-toned sagittal MRI scans of the human brain arranged together, with white technical labels overlaid.
July 8, 2021

Genetics of hydrocephalus

Fluid build-up in the brain — hydrocephalus — increases pressure and risk for brain damage; Vanderbilt researchers have now identified genes and signaling pathways associated with the condition.

VUMC NEWS logo in white lettering inside a cyan and yellow outlined square on a blue gradient background.
June 16, 2021

VUMC joins national effort to improve disease prediction in diverse populations

Vanderbilt University Medical Center will participate in a new federal initiative aimed at improving the use of polygenic risk scores (PRS) to predict complex diseases in diverse populations.

Five healthcare professionals pose outdoors in front of a building; three wear white coats, one wears a patterned blouse, and one wears blue medical scrubs.
June 3, 2021

VUMC team discovers new genetic disease

Researchers at Vanderbilt University Medical Center have discovered a new genetic disease that causes a severe form of neurogenic orthostatic hypotension, a rapid drop in blood pressure upon standing that can cause fainting.