Division of Nephrology and Hypertension

October 25, 2024

Blockbuster obesity drugs also may slow kidney disease

The report supports previous clinical trials that found the GLP-1 receptor agonist drug semaglutide reduced kidney disease progression in patients with Type 2 diabetes.

By Bill Snyder
Three-dimensional imaging of kidney tubules (yellow and green noodle-like structures) under low potassium conditions, which puts the kidney into a state of metabolic overdrive and causes cardiovascular problems.
August 5, 2024

Low potassium ‘turns on’ kidney proximal tubule: study

A kidney protein that responds to low levels of blood potassium — which can cause high blood pressure and cardiovascular problems — may be a target for new therapeutics.

By Leigh MacMillan
(iStock image)
March 25, 2024

VUMC team finds potential treatment for kidney fibrosis

By Bill Snyder
March 7, 2024

Blood mutations increase risk for acute kidney injury: study

A U.S.-Canadian research collaboration led by Vanderbilt University Medical Center has identified common, age-associated changes in the blood as a risk factor for acute kidney injury, which occurs in more than 1 in 5 hospitalized adults worldwide.

By Bill Snyder
March 4, 2024

Vanderbilt’s Yash Choksi and Fabian Bock honored by the Southern Society for Clinical Investigation

Vanderbilt’s Yash Choksi, MD, recently received the 2024 Research Investigator Early Career Faculty Award from the Southern Society for Clinical Investigation and Fabian Bock, MD, PhD, won the society’s Research Scholar Award.

By Bill Snyder
February 7, 2024

VUMC study finds molecular switch key to repair of kidney damage

Researchers at Vanderbilt University Medical Center have identified Rac1, a molecular switch that regulates the actin cytoskeleton of epithelial cells in the collecting ducts, as a driver of post-obstructive kidney repair.

By Bill Snyder
December 5, 2023

Role of immunity in kidney injury hints at a potential therapy: study

Targeting the cytokine IL-22 could be a new therapeutic approach to prevent kidney injury caused by drugs or toxins, Vanderbilt researchers have discovered.
By Bill Snyder
December 4, 2023

New study uses genetic data to support use of thiazide diuretics for kidney stone prevention

A Vanderbilt University Medical Center genetic association study of more than 1 million adults supports the use of the common blood pressure medication thiazide diuretics for kidney stone prevention.
By Danny Bonvissuto
November 21, 2023

VUMC scientists discover key step to kidney fibrosis

Researchers at Vanderbilt University Medical Center for the first time have shown that activation of the epidermal growth factor receptor (EGFR) is essential for the development of kidney fibrosis, tissue scarring following injury that can lead to kidney failure.
By Bill Snyder
October 5, 2023

Kidney disease gene also has a protective mutation

African Americans have long been known to be at increased risk of kidney disease due to a dangerous genetic mutation that creates a hole in the kidney cells, but Vanderbilt researchers have now discovered a protective genetic mutation that covers the hole to eliminate the risk.
By Craig Boerner
July 3, 2023

Vanderbilt investigators land Keck Foundation grant for groundbreaking genetic research

Vanderbilt scientists have received a $1.2 million award from the W. M. Keck Foundation for their groundbreaking project, “Genetic Intolerance Patterns as a Treasure Map to Genes that Define Us as Human.”
By VUMC News and Communications
May 23, 2023

Treating kidney injury before it happens

Pretreatment of an animal model with a novel compound called PHAD reduced kidney injury, suggesting it may be a good candidate for preventing kidney injury in surgical patients.
By Sarah E. Glass
March 2, 2023

Sex-specific regulation of kidney signals

Links between estrogen signaling and sodium excretion by the kidney could help explain a reduced risk of hypertension in females versus males.
By Kelsey Pinckard
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