Douglas Ruderfer Archive — Page 1 of 1

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May 15, 2024

Treatment-resistant depression linked to body mass index: study

Genetic factors are a small but significant contributor to severe depression that does not respond to standard therapy, according to researchers at Vanderbilt University Medical Center and Massachusetts General Hospital.

Colorful illustration of medical and laboratory equipment—including syringes, pills, a blood-pressure gauge, test tubes, a microscope, a face mask, gloves, and medicine bottles—arranged in a DNA-like strand against a yellow background.
March 27, 2024

Higher genetic risk of obesity means working out harder for same results 

Study authors used activity, clinical and genetic data from the National Institutes of Health’s All of Us Research Program to explore the association of genetic risk of higher body mass index and the level of physical activity needed to reduce incident obesity. 

Portrait of Douglas Ruderfer wearing glasses and a blue-and-white checkered shirt against a brown background.
March 8, 2024

Douglas Ruderfer to direct new Center for Digital Genomic Medicine

Douglas Ruderfer, PhD, whose research at Vanderbilt University Medical Center explores the intersection of genomics, biomedical informatics and psychiatry, has been named director of a newly established Center for Digital Genomic Medicine.

Healthcare professional in blue scrubs holding a tablet, overlaid with glowing digital medical interface graphics including a heart-monitor waveform, hearts, lungs, and connected data points.
October 13, 2022

Study to search EHR for undiagnosed genetic diseases

A team at Vanderbilt University Medical Center will explore computational solutions to help address the problem of missed or delayed diagnosis for patients with rare genetic diseases.

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November 30, 2021

Study examines genetic risk for suicide attempt

New research from Vanderbilt identifies the first replicated genomic region contributing to risk of suicide attempt and confirms that genetic risk for the trait is not driven solely by risk for psychiatric disorders.

Two men stand indoors in front of large windows; the man on the left wears glasses and a purple checkered shirt, while the man on the right wears glasses and a light gray shirt.
June 3, 2021

Predictive model identifies patients for genetic testing

Patients who, perhaps unbeknownst to their health care providers, are in need of genetic testing for rare undiagnosed diseases can be identified en masse based on routine information in electronic health records (EHRs), a research team reported June 3 in the journal Nature Medicine.