drug repurposing Archive — Page 2 of 2

February 19, 2020

Vanderbilt University Medical Center among top 100 proposals for MacArthur Foundation $100 million grant

The John D. and Catherine T. MacArthur Foundation today unveiled a grant proposal from Vanderbilt University Medical Center (VUMC) as one of the highest-scoring proposals, designated as the “Top 100,” in its 100&Change competition for a single $100 million grant to help solve one of the world’s most critical societal challenges.

September 24, 2019

Treating C. diff: new purpose for an old drug?

An inexpensive generic drug once used to prevent gastrointestinal ulcers in people taking daily NSAIDs protects against C. diff infection in mice.

July 8, 2019

Clinical study tests drug that may prevent cancer metastasis

A clinical study of a drug that may block cancer metastasis is currently enrolling patients at the Vanderbilt-Ingram Cancer Center.

April 19, 2018

VUMC drug repurposing initiative gaining momentum

Drug repurposing involves establishing an additional approved indication for a drug already at market.

Illustration of human intestinal tract
March 22, 2018

Grant bolsters study of potential new therapy for C. diff infection

According to the Centers for Disease Control and Prevention, in 2011 in the United States there were almost half a million Clostridium difficile infections, and one in 11 patients 65 or older with a healthcare-associated C. diff infection died within 30 days of diagnosis.

interior of home medicine cabinet
September 15, 2016

Study explores anti-viral potential of existing drugs

Emerging viral infections like Zika keep popping up around the world in such quick succession that medicine is having a hard time keeping up. It can take 15 years and more than a billion dollars to bring a new drug to market.