Antibiotic-resistant bacteria can share resources to cause chronic infections, Vanderbilt investigators have discovered. The findings shed light on a long-standing question in infectious diseases and may inform new treatment strategies.
Vanderbilt researchers have identified a new signaling system that anthrax bacteria uses to infect its host.
Vanderbilt University has been awarded a Cooperative Agreement with the Defense Advanced Research Projects Agency and the Army Research Office that is worth up to $16.5 million over five years.
Osteomyelitis, a debilitating bone infection most frequently caused by Staphylococcus aureus (“staph”) bacteria, is particularly challenging to treat.
Vanderbilt investigators report new insights to the workings of calprotectin, an immune system protein that “starves” bacterial pathogens of the metal nutrients they require.
It may be possible to fight hospital-acquired pathogens like Acinetobacter baumannii by targeting the bacterium’s need for the nutrient metal zinc.
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