inflammation Archives

A new contributor to atherosclerosis

Jan. 27, 2020—Sean Davies and colleagues are exploring lipid aldehydes produced during oxidative stress and their contribution to HDL dysfunction and atherosclerosis.

Insights on diabetic retinopathy

Jan. 23, 2020—A drug that targets multiple pathogenic steps in diabetic retinopathy may be an ideal therapeutic strategy for the disease, Vanderbilt researchers report.

Reversing stress-related anxiety

Dec. 20, 2019—Inhibiting COX-2 — an enzyme associated with inflammation — could provide a novel therapeutic approach for stress-related psychiatric disorders.

Endotoxin shock protector

Nov. 5, 2019—A novel tool developed by Vanderbilt scientists protects animals from endotoxin shock and can be used for mechanistic analyses of inflammation due to microbial and other insults.

Less inflammation = better healing

Oct. 17, 2019—Immune cells that produce an anti-inflammatory factor are enriched in fat tissue around the heart and may be good targets to improve heart attack outcomes.

3d rendering white blood cells with red blood cells

A new regulator of B cell development

Oct. 8, 2019—New findings establish a role for the pro-inflammatory molecule IL-33 in the early development of antibody-producing B cells.

Pua lands NIH Director’s New Innovator Award

Oct. 1, 2019—Heather Pua, MD, PhD, one of 60 investigators to receive the 2019 NIH Director’s New Innovator Award, will explore a novel type of cell signaling by RNAs in allergic airway inflammation.

The organ-on-a-chip device used by Osteen’s lab allows a constant flow of fluids that more accurately represents human internal organ systems.

Study seeks factors that increase risk of toxicant exposure

Sep. 19, 2019—Vanderbilt researchers hope to identify factors that may make humans more susceptible to toxicant exposure — specifically the presence of pre-existing inflammatory disease.