Janet Markle Archive — Page 1 of 1

Scientific illustration of a DNA double helix with a glowing highlighted section, surrounded by faint chromosome shapes on a blue background.
June 15, 2026

Study identifies genetic cause for rare skin condition, points to new therapeutic option

The research highlights the value of studying rare genetic diseases to uncover fundamental immunological mechanisms.

By Leigh MacMillan
Jeffrey Rathmell and Andrew Patterson stand together in a laboratory surrounded by shelves, containers, and scientific equipment.
August 16, 2024

Rare diseases point to connections between metabolism and immunity

Science Immunology study suggests a new class of inborn errors of immunometabolism and could improve care for patients with these complex diseases.

By Leigh MacMillan
Stylized close-up of dark molecular ball-and-stick structures against a bright blue-white background.
June 27, 2023

Rare disorder sheds light on dysbindin function

A case study of a rare disorder uncovers roles for the protein dysbindin in the adaptive immune response and suggests that mutations may underlie some cases of very early onset inflammatory bowel disease.

By Sarah E. Glass