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Jonathan Mosley Archives

For more precise drug treatments, ‘squeeze’ the genome: study finds

Jul. 22, 2021—Large-scale studies will be required to identify the complexity of genetic variations that affect how patients respond to a given drug and whether they will have side effects, according to researchers at Vanderbilt University Medical Center.

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Gene variant linked to unnecessary bone marrow biopsies in African Americans

Jun. 28, 2021—A gene variant that lowers white blood cell levels and is common in individuals with African ancestry contributes to unnecessary bone marrow biopsies, according to a study published June 28 in JAMA Internal Medicine.

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Study finds certain genetic test not useful in predicting heart disease risk

Feb. 27, 2020—A Polygenic Risk Score — a genetic assessment that doctors have hoped could predict coronary heart disease (CHD) in patients — has been found not to be a useful predictive biomarker for disease risk.

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Research bolsters thyroid function, atrial fibrillation link

Jan. 31, 2019—A study by researchers at Vanderbilt University Medical Center has strengthened the link between thyroid function and atrial fibrillation (AF), an irregular heart rhythm that increases the risk of stroke and other heart-related complications.

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Team’s study reveals hidden lives of medical biomarkers

Oct. 11, 2018—What do medical biomarkers do on evenings and weekends, when they might be considered off the clock?

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Researchers chart new informatics path in tracking disease risk

Feb. 23, 2017—In a study in Circulation: Cardiovascular Genetics, Vanderbilt University’s Jonathan Mosley, M.D., Ph.D., and colleagues use genetic correlation to hitch together two unrelated sets of data, one from a longstanding epidemiological cohort and the other from electronic health records.

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