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Journal of Allergy and Clinical Immunology Archives

Food allergy linked to lower risk of SARS-CoV-2 infection

Jun. 3, 2022—  by Nancy Humphrey People with food allergies are surprisingly less likely to become infected with SARS-CoV-2, the virus that causes COVID-19, than people without them, a study funded by the National Institutes of Health and co-led by Vanderbilt University Medical Center’s Tina Hartert, MD, MPH, has found. In addition, the Human Epidemiology and Response...

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‘Friendly’ bacteria may impact COVID severity

Mar. 11, 2021—The U.S. Centers for Disease Control and Prevention (CDC) has awarded Vanderbilt University Medical Center a two-year, $3.7-million contract to determine genetic and bacterial factors that may increase the risk for severe illness and death from COVID-19.

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Gene identified that increases risk of antibiotic reaction

Feb. 28, 2019—Researchers at Vanderbilt University Medical Center and colleagues have identified a gene that increases the risk for a severe and potentially life-threatening reaction to the commonly prescribed antibiotic vancomycin.

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Study finds unique form of chronic sinusitis in older patients

Jan. 17, 2019—Older patients with a diagnosis of chronic sinusitis — a disease of the nasal cavity and paranasal sinuses that often persists over many years — have a unique inflammatory signature that may render them less responsive to steroid treatment, according to a new study published by Vanderbilt researchers.

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Connecting an asthma gene to leukemia

Aug. 2, 2018—A receptor previously implicated in asthma may also play roles in other allergic diseases and in leukemia, Vanderbilt researchers have discovered.

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Team explores diabetes drug’s ability to treat RSV infection

Jul. 12, 2018—A drug used to treat diabetes may point to new therapies for respiratory syncytial virus (RSV) bronchiolitis — inflammation and obstruction of the lungs’ small airways. A multi-disciplinary team of Vanderbilt investigators has demonstrated that liraglutide reduces the inflammatory response to RSV infection in a mouse model of the disease.

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Study of mucus may help guide sinusitis treatment

Mar. 29, 2018—A patient’s mucus may predict the type of his or her chronic sinusitis, which could help doctors determine whether surgery or medical treatments can produce the best outcomes, according to a recently published Vanderbilt study.

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Study sheds light on how childhood RSV can lead to asthma

Mar. 1, 2018—Infants who have higher amounts of the bacterium Lactobacillus present in their nose or upper part of the throat during an acute respiratory syncytial virus (RSV) infection are less likely to develop childhood wheezing later in life, a new Vanderbilt-led Center for Asthma Research study found.

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Aspirin and allergies

Oct. 10, 2014—Drugs such as aspirin and indomethacin may increase sensitivity to airborne allergens by suppressing production of the signaling molecule PGI2, which in turn may offer a new treatment for allergies.

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