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Journal of Biological Chemistry Archives

Liver balancing act

Feb. 24, 2016—Vanderbilt researchers have defined a mechanism that limits liver cell proliferation after injury in order to preserve critical metabolic functions.

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Faulty building blocks in DNA

Jan. 22, 2016—An enzyme that builds DNA is able to insert the wrong building blocks, which could generate mutations.

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Rational design of novel antifungals

Oct. 7, 2015—Structural and molecular details of an anti-fungal target's interaction with inhibitors suggest ways to design better treatments for fungal infections.

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How to build a basement

Sep. 9, 2015—Understanding the action of a certain enzyme will shed light on basement membrane function, and on disorders ranging from diabetic kidney disease to cancer.

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Vitamin C protects blood vessel lining

Sep. 4, 2015—Dietary vitamin C may maintain healthy blood vessels in patients with inflammatory diseases.

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How the cell makes morphine

Aug. 25, 2015—Vanderbilt investigators have discovered how mammals, including humans, produce the painkiller morphine.

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Guengerich named interim editor of noted journal JBC

Jul. 9, 2015—Vanderbilt University’s F. Peter (Fred) Guengerich, Ph.D., has been named interim editor-in-chief of the Journal of Biological Chemistry (JBC).

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New player in neuronal communication

May. 1, 2015—Vanderbilt researchers have discovered a novel mechanism for the development of dendritic spines – sites of nerve cell communication.

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Enzyme holds the door for influenza

Aug. 20, 2014—Compounds developed at Vanderbilt University may offer a new way to block influenza infection.

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Anti-inflammatory protein “rheostat” sheds light on leaky blood vessels

Aug. 1, 2014—Vanderbilt researchers have discovered that the protein CRADD counteracts inflammatory injury to endothelial cells, which could assist the development of new therapies for inflammatory vascular disorders.

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CaMKII enhances insulin secretion

May. 14, 2014—The protein CaMKII acts as a calcium sensor in a positive feedback pathway that enhances glucose-stimulated insulin secretion.

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Bypassing DNA damage

May. 9, 2014—Studies of a human polymerase that replicates DNA have provided a complete kinetic and structural framework for understanding how the enzyme accurately bypasses DNA damage.

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