Journal of Biological Chemistry Archives
Liver balancing act
Feb. 24, 2016—Vanderbilt researchers have defined a mechanism that limits liver cell proliferation after injury in order to preserve critical metabolic functions.
Faulty building blocks in DNA
Jan. 22, 2016—An enzyme that builds DNA is able to insert the wrong building blocks, which could generate mutations.
Rational design of novel antifungals
Oct. 7, 2015—Structural and molecular details of an anti-fungal target's interaction with inhibitors suggest ways to design better treatments for fungal infections.
How to build a basement
Sep. 9, 2015—Understanding the action of a certain enzyme will shed light on basement membrane function, and on disorders ranging from diabetic kidney disease to cancer.
Vitamin C protects blood vessel lining
Sep. 4, 2015—Dietary vitamin C may maintain healthy blood vessels in patients with inflammatory diseases.
How the cell makes morphine
Aug. 25, 2015—Vanderbilt investigators have discovered how mammals, including humans, produce the painkiller morphine.
Guengerich named interim editor of noted journal JBC
Jul. 9, 2015—Vanderbilt University’s F. Peter (Fred) Guengerich, Ph.D., has been named interim editor-in-chief of the Journal of Biological Chemistry (JBC).
New player in neuronal communication
May. 1, 2015—Vanderbilt researchers have discovered a novel mechanism for the development of dendritic spines – sites of nerve cell communication.
Enzyme holds the door for influenza
Aug. 20, 2014—Compounds developed at Vanderbilt University may offer a new way to block influenza infection.
Anti-inflammatory protein “rheostat” sheds light on leaky blood vessels
Aug. 1, 2014—Vanderbilt researchers have discovered that the protein CRADD counteracts inflammatory injury to endothelial cells, which could assist the development of new therapies for inflammatory vascular disorders.
CaMKII enhances insulin secretion
May. 14, 2014—The protein CaMKII acts as a calcium sensor in a positive feedback pathway that enhances glucose-stimulated insulin secretion.
Bypassing DNA damage
May. 9, 2014—Studies of a human polymerase that replicates DNA have provided a complete kinetic and structural framework for understanding how the enzyme accurately bypasses DNA damage.
