Journal of Clinical Investigation Archive — Page 2 of 4
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January 25, 2018
Study may point to new ways to reverse insulin resistance
Researchers at Vanderbilt University have discovered how insulin crosses the capillary endothelium to exit blood vessels and stimulate skeletal muscle cells — a major finding that may lead to new ways to reverse insulin resistance, a hallmark of type 2 diabetes. -
May 25, 2017
Study reveals role for stem cells in chronic lung diseases
A novel population of lung stem cells plays an important role in regulating the pulmonary microvasculature — the network of tiny blood vessels where oxygen and carbon dioxide exchange takes place. -
April 18, 2017
Vanderbilt-led study shows high-salt diet decreases thirst, increases hunger
Salted peanuts make you thirsty so you drink more: that’s bartender wisdom. While that may be true in the short-term, within 24 hours increasing salt consumption actually makes you less thirsty because your body starts to conserve and produce water. -
October 13, 2016
EGF receptor found to regulate macrophage inflammation in gut
Researchers at Vanderbilt University School of Medicine have uncovered a link between epidermal growth factor receptor (EGFR) signaling and the inflammatory response to bacterial infection in the gastrointestinal tract. -
April 28, 2016
Study sheds light on link between autism, GI issues
Researchers at Columbia and Vanderbilt universities have made an important discovery in mice that has implications for understanding the gastrointestinal (GI) problems experienced by some children with autism. -
January 27, 2016
Study identifies new culprit in lung cancer development
A microRNA — a small piece of RNA involved in regulating gene expression — functions as an oncogene to drive the development of lung cancer, Vanderbilt University investigators have discovered. -
October 22, 2015
Study sheds light on side effects of COX-2 drugs
A team of Vanderbilt University Medical Center scientists are closer to understanding why COX-2 inhibitors — drugs that relieve arthritis pain and inflammation without the gastrointestinal side effects of other painkillers — cause heart problems in some patients. Now