Journal of Clinical Investigation

April 3, 2014

Protein’s role in spread of colon cancer studied

One of the most formidable weapons in a cancer’s arsenal is the ability to spread to other organs.

By VUMC News and Communications
March 19, 2014

Small molecule protects kidney filter

A compound identified at Vanderbilt has therapeutic potential in protecting the kidney filter barrier.

By Bill Snyder
February 20, 2014

Studies shed new light on breast cancer development

Rebecca Cook, Ph.D., assistant professor of Cancer Biology, has spent her life trying to understand what makes things grow, from seedlings in soil to tumor cells in the body.

By VUMC News and Communications
September 17, 2013

Researchers identify novel biomarker for diabetes risk

Researchers at the Vanderbilt Heart and Vascular Institute and Massachusetts General Hospital have identified a biomarker that can predict diabetes risk up to 10 years before onset of the disease.

By Kathy Whitney
June 6, 2013

Study tracks skin salt’s role in blood pressure control

Clinical pharmacologist Jens Titze, M.D., and his colleagues have identified a new cast of cells and molecules that function in the skin to control sodium balance and blood pressure.

By Leigh MacMillan
May 30, 2013

Study lays groundwork for rational T cell vaccine design

Vanderbilt University investigators have developed a new strategy for identifying the “bits” of a pathogen that spark a protective immune response.

By Leigh MacMillan
March 21, 2013

Breast cancer study explores therapy to slow recurrence

Many patients with triple-negative breast cancer (TNBC) have recurrence of their disease after an initial response to chemotherapy because the cancer cells have become resistant to treatment. TNBC has a lower survival rate because of this pattern of resistance and there are no targeted agents to treat this form of breast cancer.
By VUMC News and Communications
February 6, 2013

Linking oxygen, iron and red blood cells

The HIF oxygen-sensing pathway and its responses to low oxygen may be targeted for treatments of anemia and disorders of iron balance.
By Leigh MacMillan
January 31, 2013

Do-it-yourself repair in the kidney

The kidney can mediate its own repair through proliferation of resident immune system cells.
By Leigh MacMillan
August 9, 2012

New therapeutic target for cold, flu viruses identified

Viruses that cause acute respiratory infections — such as human metapneumovirus (HMPV) and flu — impair a set of immune system cells that should clear the virus from the lungs. Now, Vanderbilt University investigators have discovered the signaling pathway that disables these immune cells.
By Leigh MacMillan
October 7, 2011

Heart protein may be target for colon cancer therapies

A protein critical in heart development may also play a part in colon cancer progression.
By VUMC News and Communications