MacRae Linton

August 19, 2021

Potential protection from atherosclerosis

Vanderbilt researchers have discovered a potential way to reduce atherosclerosis: blocking the modification of an HDL-associated enzyme by reactive molecules called isolevuglandins.

By Bill Snyder
From left, MacRae Linton, MD, Huan Tao, MD, PhD, Jonathan Brown, MD, and colleagues have discovered a potential new target for preventing atherosclerosis.
July 8, 2021

Nature’s “recycler” could reduce heart disease risk: study

Researchers at Vanderbilt University Medical Center have identified potential new targets for the prevention of atherosclerosis through the enhancement of autophagy, a natural process for recycling damaged cellular material.

By Bill Snyder
Cholesterol
January 21, 2021

NIH grant bolsters research on heart disease, cholesterol

Thanks to major funding from the National Institutes of Health (NIH), researchers at Vanderbilt University Medical Center have made major inroads in understanding how high-density lipoprotein (HDL), commonly known as good cholesterol, in some cases may actually contribute to the development of atherosclerosis.

By Bill Snyder
From left, Huan Tao, MD, PhD, Sean Davies, PhD, Jiansheng Huang, PhD, and MacRae Linton, MD, led the study that identified a potential new treatment for atherosclerosis.
August 20, 2020

‘Scavenger’ molecule may point to new atherosclerosis treatment

A small-molecule “scavenger” that reduces inflammation and formation of atherosclerotic plaque in blood vessels in mice potentially could lead to a new approach for treating atherosclerosis in humans, according to researchers at Vanderbilt University Medical Center.

By Bill Snyder
From left, Ryan Allen, PhD, MacRae Linton, MD, Kasey Vickers, PhD, Quanhu Sheng, PhD, and colleagues are working to create a new model of atherosclerosis development. (photo by Susan Urmy)
August 26, 2019

VUMC investigators receive Keck Foundation award for novel atherosclerosis research

A team of researchers has received a $1 million grant from the W.M. Keck Foundation to explore a novel model of atherosclerosis development.

By Leigh MacMillan
November 25, 2014

Protein implicated in atherosclerosis

Vanderbilt researchers have discovered a new target for the prevention of atherosclerotic plaque development and cardiovascular disease.

By VUMC News and Communications
September 18, 2014

Prevention key to fight familial hypercholesterolemia

Imagine an inherited cause of early heart attacks that is more common than type-1 diabetes, multiple sclerosis or cystic fibrosis, but goes largely unrecognized.
By Matt Batcheldor
August 21, 2014

Major grant spurs deeper look into ‘good cholesterol’

In some cases, HDL, the "good cholesterol," may not function properly and may actually accelerate atherosclerosis.
By Bill Snyder
November 25, 2013

Vanderbilt celebrates 18 elected fellows of the AAAS

Eighteen academic and administrative leaders at Vanderbilt University have been elected fellows of the American Association for the Advancement of Science (AAAS) this year.
By Bill Snyder