nanobody Archive — Page 1 of 1

White alpaca standing in a grassy field at the edge of a wooded area, facing the camera.
April 28, 2026

Warm Fleece Meets Cool Science

Alpacas unlock potential of tiny but powerful nanobodies. Today, alpacas are fueling nanobody research across the Vanderbilt campus and around the world.

By Bill Snyder
Fluorescence microscopy comparison labeled “Control” and “AD”: bright amyloid oligomer signal follows a retinal vessel in the control panel, while the AD panel shows weaker, more diffuse signal. Scale bar: 20 µm.
April 7, 2026

Multi-institutional team pioneers retinal test for early Alzheimer’s disease

The potential for a retinal screening test was bolstered by a recent discovery that clearance of amyloid-beta oligomers by immune cells in retinal blood vessels was disrupted in donor eyes from individuals with Alzheimer’s disease, compared to age-matched, healthy control eyes.

By Bill Snyder
C. difficile bacteria (image courtesy of CDC/Jennifer Oosthuizen)
February 18, 2026

Vanderbilt research offers new hope for preventing repeated C. diff infections

Treatment options are limited for the more than 500,000 people in the U.S. who are diagnosed annually with C. diff infections, but researchers are working on potential vaccines, therapeutic antibodies and — most recently — nanobodies, to prevent and treat C. diff infections.

By Bill Snyder
Two researchers stand in a laboratory beside shelves of scientific supplies and equipment.
February 16, 2024

Waddell Walker Hancock Cancer Discovery Fund names first scholars

A research endeavor that seeks to develop a new cancer immunotherapy utilizing nanobody delivery and targeted heating of tumors has received funding from the Waddell Walker Hancock Cancer Discovery Fund.

By Tom Wilemon