Nature Cell Biology (journal)

The study could suggest ways to promote the transport of phospholipids and cholesterol out of macrophages, immune system cells that play key roles in all stages of atherosclerosis development.
January 19, 2023

Study points to new ways to prevent, treat heart disease

Vanderbilt researchers have confirmed the existence of an alternative pathway to atherosclerosis, a finding that may lead to new ways to prevent and treat cardiovascular disease.

By Bill Snyder
PHOTO: Members of the supermere discovery team include (front row from left) Qi Liu, PhD, Robert Coffey, MD, Qin Zhang, PhD, and (back row from left) James Higginbotham, PhD; Dennis Jeppesen, PhD; and Jeffrey Franklin, PhD. (hoto by Erin O. Smith)
December 10, 2021

“Supermeres” may carry clues to cancer, Alzheimer’s disease and COVID-19

Vanderbilt researchers have discovered a nanoparticle released from cells, called a “supermere,” which contains enzymes, proteins and RNA associated with multiple cancers, cardiovascular disease, Alzheimer’s disease and even COVID-19.

By Bill Snyder
October 21, 2016

DNA damage response protein

Vanderbilt researchers have determined that a previously uncharacterized protein responds to DNA replication stress and has an essential role in maintaining the integrity of the genome.

By Bill Snyder
July 17, 2014

Breast tissue growth protein may promote cancer: study

A protein essential for growth of normal breast tissue also may play a role in breast cancer, Vanderbilt University researchers have found.

By Bill Snyder