Neurobiology of Aging (journal)

How arterial “stiffness” may impair cognition

New findings from Vanderbilt neurologists suggest that cardiovascular disease may increase the spaces surrounding blood vessels in the brain and lead to cognitive decline.

Alzheimer’s risk factor and cognition

Vanderbilt researchers found that a protein with roles in innate immunity worsens memory at baseline in carriers of APOE-e4, the strongest genetic risk factor for Alzheimer’s disease, further implicating neuroinflammation in cognitive decline.

Vitamin C protects brain from seizures

Brain ascorbate — vitamin C — is important for protecting the brain against seizures and cognitive decline in Alzheimer’s disease.

Probing the pathology of impaired cognition

Detecting the neuropathology underlying cognitive impairment by lead to new targeted therapies.