New England Journal of Medicine

A study found that aspirin counteracts clotting as effectively as other treatments and is also cheaper.
February 9, 2023

Aspirin’s effectiveness at preventing blood clots studied

A Vanderbilt study found that aspirin is as effective as low molecular weight heparin at preventing hospital-acquired deep venous thromboembolism, or blood clots in the veins, for orthopaedic trauma patients.

By Danny Bonvissuto
Wesley Self, MD, MPH
February 2, 2023

Study of two sepsis interventions finds identical outcomes

Vanderbilt University Medical Center had a leading role in a large national study designed to compare two early interventions in the treatment of patients with sepsis, the body’s severe response to an uncontrolled infection.

By Nancy Humphrey
November 10, 2022

Study defines role of steroids in congenital heart disease surgery

Steroids are commonly given to infants during open-heart surgery to reduce inflammation, but whether the drugs significantly improve patient outcomes has not been settled — until now.

By Bill Snyder
November 4, 2022

Study finds Moderna’s COVID-19 vaccine safe and effective for young children

A Vanderbilt study finds that Moderna’s COVID-19 vaccine is safe and effective in children 6 months to 5 years of age.

By Bill Snyder
October 24, 2022

Vanderbilt study finds that the most common oxygen saturation targets for hospitalized patients appear equally safe and effective

A Vanderbilt study looked at the oxygen saturation target that results in optimal outcomes — number of days alive and free of mechanical ventilation — in 2,500 critically ill adults receiving mechanical ventilation.

By Nancy Humphrey
July 6, 2022

Study shows two vaccine doses for mothers eases COVID complications for infants

Infants younger than 6 months were better protected from COVID-19 complications when mothers received two doses of the vaccine while pregnant, according to Vanderbilt researchers.

By Jessica Pasley
June 8, 2022

Research probes cause of acute flaccid myelitis in children

Research that began at Vanderbilt University Medical Center has found evidence that a viral infection followed by a “robust” immune response is the cause of a polio-like paralyzing illness in children called acute flaccid myelitis (AFM).
By Bill Snyder
May 12, 2022

VUMC-led study finds Moderna COVID vaccine safe and effective for children

By Bill Snyder
May 10, 2022

New study illustrates how much it would cost for cancer drugs covered under Medicare Part D

A new study by Vanderbilt researchers highlights how some older Americans diagnosed with cancer can face unlimited out-of-pocket spending for prescription drugs under the current structure of the Medicare Part D benefit.
By Jake Lowary
December 8, 2021

International study supports dupilumab for treatment of moderate-to-severe asthma in children

In a late-stage clinical trial, the biologic agent dupilumab reduced the rate of severe asthma attacks and improved lung function and asthma control for children ages 6 to 11 with moderate-to-severe asthma, offering a new option to these patients.
By Leigh MacMillan
May 20, 2021

VUMC is pacesetter for national aspirin study

According to an innovative large-scale clinical trial reported last week in the New England Journal of Medicine, a single daily baby aspirin (81 mg) or a single daily adult aspirin (325 mg) are equally safe and effective for prevention of adverse cardiovascular events for patients with established atherosclerotic cardiovascular disease.
By Paul Govern
April 22, 2021

A young doctor wrote of a life-or-death moment caring for a patient. The New England Journal of Medicine published it as a graphic novel.

A terrifying tale from her first weekend on call.
By Emily Stembridge
February 2, 2021

Study finds recommended ICU sedatives equally safe, effective

Sedative medications used in intensive care are associated with increased delirium, which is in turn connected with higher medical costs and greater risk of death and ICU-related dementia.
By Paul Govern