New England Journal of Medicine Archives
Study identifies targeted therapy’s cardiac risks
Sep. 25, 2019—After a recent study showed that chronic lymphocytic leukemia patients who received ibrutinib as a frontline treatment had a 7% death rate, a new study offers a clearer picture on the reasons for the deaths.
All-in-one pill helps reduce blood pressure, cholesterol
Sep. 19, 2019—A single pill containing low doses of three medications to treat high blood pressure and one to lower cholesterol reduced the estimated risk of cardiovascular disease by 25%, according to a VUMC study.
All of Us Research Program Takes Aim at Precision Population Health
Aug. 14, 2019—Scarcely a year after its national launch, the “All of Us” research program, which aims to accelerate the prevention and treatment of disease, has enrolled more than 230,000 research participants — more than a fifth of its recruitment goal of 1 million people. All
VUMC study finds helping patients breathe during intubation prevents life-threatening complications
Feb. 18, 2019—Thousands of Americans die each year during a dangerous two-minute procedure to insert a breathing tube. Now a Vanderbilt University Medical Center (VUMC) study in the New England Journal of Medicine (NEJM) is showing that using bag-mask ventilation, squeezing air from a bag into the mouth for 60 seconds to help patients’ breathing, improves outcomes and could potentially save lives.
Combination therapy improves small-cell lung cancer survival
Oct. 25, 2018—Patients with stage IV small-cell lung cancer lived longer when given the immunotherapy atezolizumab with chemotherapy, setting the stage for what could become the first new treatment approved in decades for this particularly aggressive form of lung cancer.
Antipsychotics ineffective for treating ICU delirium: study
Oct. 22, 2018—Critically ill patients are not benefiting from antipsychotic medications that have been used to treat delirium in intensive care units (ICUs) for more than four decades, according to a study released today in the New England Journal of Medicine.
Time window extended for some stroke surgeries
Mar. 1, 2018—New research indicates the time window for a thrombectomy following a stroke is longer than previously thought, but how soon the surgery occurs still matters.
Saline use on decline at Vanderbilt following landmark studies
Feb. 27, 2018—Vanderbilt University Medical Center is encouraging its medical providers to stop using saline as intravenous fluid therapy for most patients, a change provoked by two companion landmark studies released Feb. 27 that are anticipated to improve survival and decrease kidney complications.
Team finds stem cell transplant improves scleroderma survival
Feb. 15, 2018—A new clinical trial by investigators at Vanderbilt University Medical Center (VUMC) and other leading medical centers found that an intensive transplant treatment using the patient’s own stem cells can improve survival and quality of life for patients with advanced scleroderma.
NEJM Catalyst forum addresses mental, behavioral and social health determinants
Jan. 29, 2018—Healthcare is more than diagnosing and treating disease. To truly improve health outcomes for individuals and communities, the mental, behavioral and social determinants of health must be fully integrated with physical factors at all levels of the healthcare system.
New lab formulary improves quality, cuts cost
Sep. 21, 2017—An effort at Vanderbilt University Medical Center (VUMC) to enhance clinical decision making through cross-departmental collaboration and effective use of diagnostics has improved patient care and saved the institution more than $1 million in 2016, VUMC officials reported this week.
New approach for staph-related skin abscesses explored
Jul. 13, 2017—New multicenter research that includes Vanderbilt University Medical Center (VUMC) investigators, could change treatment approaches to simple skin abscesses, infections often caused by Staphylococcus aureus (staph) bacteria.
